Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Antifungal Activity of 4-Geranyloxy Compound on the Dermatophytic Fungus

  • Oh Hyun Ju (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwng University) ;
  • You Byung Soo (Division of Natural Sciences, Wonkwng University) ;
  • Kim Myung Ju (Department of Skin & Beauty, Kwangju Health Science College,) ;
  • Na Young Soon (Division of Fashion & Beauty, Konyang University) ;
  • Kim Hyung Min (Department of Pharmacology, School of Oriental Medicine, Kyunghee University) ;
  • Baek Seung Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwng University)
  • Published : 2004.04.01
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Abstract

4-Geranyloxy compound (1) has elucidated by spectroscopic analysis. This compound (1) inhibited the growth of the dermatophytic fungus Trichophyton mentagrophytes ATCC 28185, (2 mm inhibition zone at 15 ㎍/disc), cytotoxic to P388 murine leukaemia eel/lines ATCC CCL 46 P388D1, (IC/sub 50/ 1,125 ng/ml at 7.5㎍/disc) and BSC monkey kidney cell lines (100% of well at 15 ㎍/disc).

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