Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Study on the Polyphosphate content of the Yukmijihwang-tang and its Effect on transcription activity of Genes related to Bone Morphogenesis

육미지황탕의 인중합체 함량과 골형성 관련 유전자의 전사활성에 대한 연구

  • Park Byung Chul (Department of oriental Rehabilitation Medicine, College of Oriental Medicine, Sang-ji University) ;
  • Cha Yun Yeop (Department of oriental Rehabilitation Medicine, College of Oriental Medicine, Sang-ji University) ;
  • Lee Eung Se (Department of oriental Rehabilitation Medicine, College of Oriental Medicine, Sang-ji University)
  • 박병철 (상지대학교부속 한방병원 한방재활의학교실) ;
  • 차윤엽 (상지대학교부속 한방병원 한방재활의학교실) ;
  • 이응세 (상지대학교부속 한방병원 한방재활의학교실)
  • Published : 2004.12.01
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Abstract

The aim of this study was to find out the effects of the Yukmijihwangtang on transcription activity of Genes related to Bone Morphogenesis. For this purpose, experiments were performed to compare the polyphosphate contents of Yukmijihwangtang and its component herbs, and to verify their Effects on transcription activity of Genes related to Bone Morphogenesis. We know that Yukmijihwangtang and its component herbs have adequate amount of polyphosphate contents and have effects on transcription activity of Genes such as BMP1A, BMP2B, OTN, MGP, COL. In the conclusion, Yukmijihwangtang and its component herbs are strongly believed to have effectiveness on bone morphogenesis.

Keywords

References

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