참고문헌
- Adari, H., Lowy, D. R., Willumsen, B. M., Der, C. J., and McCormick, F., Guanosine triphosphate activating protein (GAP) interacts with the p21 ras effector binding domain. Science, 240, 518-521 (1988) https://doi.org/10.1126/science.2833817
- Cho, S. J., Garsia, M. L. S., Bier, J., and Tropsha, A., Structurebased alignment and comparative molecular field analysis of acetylcholinesterase inhibitors. J. Med. Chem., 39, 5064-5071 (1996) https://doi.org/10.1021/jm950771r
- Cho, Y. K., CoMFA on Cinnamaldehyde Analogues against FPTase Inhibitory Acitivity, Ph.D. thesis, Graduate school of Chungnam National University, Korea (2002)
- Choo, H.-Y. P., Choi, S., Ryu, C.-K., Kim, H.-J., Lee, I. Y., Pae, A. N., and Koh, H. Y., QSAR study of quinolinediones with inhibitory activity of endothelium-dependent vasorelaxation by CoMSIA. Bioorg. Med. Chem., 11,2019-2023 (2003) https://doi.org/10.1016/S0968-0896(03)00045-2
- Forina, M., Casolino, C., and Millan, C. P., Iterative predictor weighting (IPW) PLS: a technique for the elimination of useless predictors in regression problems. J. Chemometr, 13,165-184 (1999) https://doi.org/10.1002/(SICI)1099-128X(199903/04)13:2<165::AID-CEM535>3.0.CO;2-Y
- Gibbs, J. B. and Oliff A., Pharmaceutical research in molecular oncology. Cell, 79,193-198 (1994) https://doi.org/10.1016/0092-8674(94)90189-9
- Huang, M., Yang, D.-Y., Shang, Z., Zou, J., and Yu, Q., 3DQSAR studies on 4-hydroxyphenylpyruvate dioxygenase inhibitors by comparative molecular field analysis (CoMFA). Bioorg. Med. Chem. Lett., 12,2271-2275 (2002) https://doi.org/10.1016/S0960-894X(02)00432-8
- Knight, D. W., Feverfew: chemistry and biological activity. Nat. Prod. Rep., 12,271-276 (1995) https://doi.org/10.1039/np9951200271
- Kwon, B. M., Cho, Y. K., and Lee, S. H., 2'-Hydroxycinnamaldehyde from stem bark of Cinnamomum cassia. Planta Medica, 62,183-184 (1996) https://doi.org/10.1055/s-2006-957851
- Kwon, B. M., Lee, S. H., Cho, Y. K., Bok, S. H., So, S. H., Youn, M. R., and Chang, S. I., Synthesis and biological activity of cinnamaldehyde as angiogenesis inhibitors. Bioorg. Med. Chem. Lett., 7, 2473-2476 (1997) https://doi.org/10.1016/S0960-894X(97)10008-7
- Kwon, B. M., Lee, S. H., Choi, S. U., Park, S. H., Lee, C. O., Cho, Y. K., Sung, N. D., and Bok, S. H., Synthesis and in vitro cytotoxicity of cinnamaldehyde to human solid tumor cells. Arch. Pharm. Res., 21,147-152 (1998) https://doi.org/10.1007/BF02974019
- Lindgren F, Geladi P, Rannar S, and Wold S., Interactive Variable Selection (Ivs) For Pis .1. Theory and Algorithms. J. Chemometr., 8, 349-363 (1994) https://doi.org/10.1002/cem.1180080505
- Lodish, H., Berk, A., Zipursky, S. L., Matsudaira, P., Baltimore, D., and Darnell, J., Molecular Cell Biology, W. H. Freeman and Company, New York, (1995)
- Pedretti, A., Villa, L., and Vistoli, G., Modeling of binding modes and inhibition mechanism of some natural ligands of farnesyl transferase using molecular docking. J. Med. Chem., 45, 1460-1465 (2002) https://doi.org/10.1021/jm011075w
- Podlogar, B. L., Muegge, I., and Brice, L. J., Computational methods to estimate drug development parameters. Curr. Opin. Drug Discovery Dev., 4,102-109 (2001)
- Qian, Y., Blaskovich, M. A., Saleem, M., Seong, C. M., Wathen, S. P., Hamilton, A. D., and Sebti, S. M., Design and structural requirements of potent peptidomimetic inhibitors of p21ras famesyltransferase, J. Biol. Chem., 269,12410-12413 (1994)
- Raichurkar, A. V. and Kulkarni, V. M., Understanding the antitumor activity of novel hydroxysemicarbazide derivatives as ribonucleotide reductase inhibitors using CoMFA and CoMSIA. J. Med.Chem., 46, 4419-4427 (2003) https://doi.org/10.1021/jm030016a
-
Reiss, Y., Goldstein J. L., Seabra, M. C., Casey, P.J., and Brown, M. S., Inhibition of purified
$p21^{ras}$ farnesyl:protein transferase by Cys-AAX tetrapeptides. Cell, 62, 81-88 (1990) https://doi.org/10.1016/0092-8674(90)90242-7 - Schweins, T., Geyer, M., Scheffzek, K., Warshel, A., Kalbitzer, H. R., and Witlinghofer, A., Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTPbinding proteins. Nat. Struct. Biol., 2, 36-44 (1995) https://doi.org/10.1038/nsb0195-36
- Sung, N.-D., Cheun, Y. G., Kwon, B.-M., Park, H.-Y., and Kim, C. K., Modeling of inhibition mechanism of natural ligands to famesyl protein transferase using molecular docking. Bull. Kor. Chem. Soc., 24,1509-1511 (2003) https://doi.org/10.5012/bkcs.2003.24.10.1509
- Wu, T.-S., Qu, L.-F., and Teng, C.-M., Aristolochic acids, aristolactam alkaloids and amides from Aristolochia kankauensis. Phytochemistry, 36,1063-1068 (1994) https://doi.org/10.1016/S0031-9422(00)90492-8
- Zhu, L., Hou, T., and Xu, X., Three-dimensional quantitative structure-activity relationship study on paullones as CDK inhibitors using CoMSIA and CoMFA. J. Mol. Model., 7, 223-230 (2001) https://doi.org/10.1007/s008940100017