Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Stimulation of Actinorhodin Production by Streptomyces lividans with a Chromosomally-Integrated Antibiotic Regulatory Gene afsR2

  • Kim, Chang-Young (School of Chemical Engineering and Biotechnology, Inha University) ;
  • Park, Hyun-Joo (School of Chemical Engineering and Biotechnology, Inha University) ;
  • Yoon, Yeo-Joon (Division of Nano Sciences and Department of Chemistry, Ewha Woman's University) ;
  • Kang, Han-Young (Department of Chemistry, Chungbuk National University) ;
  • Kim, Eung-Soo (School of Chemical Engineering and Biotechnology, Inha University)
  • Published : 2004.10.01
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Abstract

An actinorhodin nonproducing Streptomyces lividans was converted to an actinorhodin overproducer through a single chromosomal integration of an antibiotic regulatory gene, afsR2. This strain exhibited early actinorhodin production and an average of 37.5% higher productivity than the S. lividans containing multiple copies of afsR2 plasmid in a glucose-containing liquid culture.

Keywords

References

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