한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제21권3호
  • /
  • Pages.243-247
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  • 2004
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

개의 실험적 간모세선충증

Experimental Hepatic Capillariasis in Dogs

  • 곽동미 (워싱턴주립대학교 수의과대학) ;
  • 권오덕 (경북대학교 수의과대학)
  • 발행 : 2004.09.01
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초록

This studies was carried out to investigate a process of formation for the granulomatous lesions in the liver and the haematological variation with the lapse of time after infection of Capillaria hepatica in dogs. Twelve crossbred puppies, about 3 months of age and 2-3 kg of body weight, were administered with 2,000 Capillaria hepatica infective eggs. Every four puppies was sacrificed on 1 week, 3 weeks and 5 weeks after infection, respectively. Although no marked clinical sign was noticed, total leukocyte values were increased peak on 1 week, and then reduced gradually on 3 weeks and 5 weeks after infection. Absolute differential counts of neutrophils and lymphocytes were significantly increased on 1, 3 and 5 weeks after infection. Absolute differential counts of monocytes and eosinophils were trend to increase during the experimental periods. On grossly findings, liver congestions were observed in all infected puppies, and a few white specks were scattered under liver capsule in one puppy on 3 weeks and two puppies on 5 weeks after infection. On microscopic findings, many fresh larvae were observed in the liver tissues in one puppy on 1 week after infection. A worm was decayed and only a portion of cuticle was shown in one puppy on 3 weeks after infection. Around the central necrotic material, the layers of thick macrophages with a few giant cells and lymphocytes with fibrous connective tissues were consisted the granulomatous lesions on 5 weeks after infection.

키워드

참고문헌

  1. Anderson RC. Nematode parasites of vertebrates; Their development and transmission. CAB Internat 1992: 546-548
  2. Attah EB, Nagarajan S, Obineche, EN, Gera SC. Hepatic caillariasis. Am J Clinic Pathol 1983; 79: 127-130
  3. Berger T, Degremont A, Gebbers JO, Tonz, O. Hepatic capillariasis in a 1-year old child. Eur J Pediatr 1990; 149: 333-336 https://doi.org/10.1007/BF02171560
  4. Brander P, Denzler T, Henzi M. Capillaria hepatica bei einem Hund und einem Igel. Schweiz Arch Tierheilk 1990; 132: 365-370
  5. Choe GY, Lee HS, Seo Jk, Chai JY, Lee SH, Eom KS, Chi JG. Hepatic capillariasis; First case report in the Republic of Korea. Am J Trop Med Hyg 1993; 48: 610-625
  6. Chung YW, Eom KS, Rim HJ. Comparative studies on the immunodiagnosis of Capillaria hepatica infection in white rats with egg antigens. Dept Parasitol and Institute Trop Endemic Disease, College of Med, Korea Univ 1985; 22: 43-52
  7. Crowell WA, Klei TR, Hall DI, Smith NK, Newson JD. Capillaria hepatica infection in coyotes of Louisiana. J Am Vet Med Asso 1978; 173: 1171-1172
  8. Junker-Voss M, Prosl H, Lussy H, Enzenberg U, Auer H, Nowotny N. Serological detection of Capillaria hepatica by dndirect immunofluorescence assay. J Clini Microbio 2000; 38: 431-433
  9. Kim JH, Hwang EK, Jean YH, Bae YC, Kim DY, Yoon YD, Choi SH. Pathological findings of Capillaria hepatica infection in dogs. Kor J Vet Publ Hlth 1995; 19: 123-130
  10. Kutzer E, Frey H. Die Parasiten der Feldhasen(Lepus europaeus) in Osterreich. Berl Munch Tierarztl Wschr 1976; 89: 480-483.
  11. Layne JN, Winegarner CE. Occurrence of Capillaria hepatica(Nematode: Trichuridae) in the spotted skunk in Florida. J Wildl Dis 1971; 7: 256-257
  12. LeBlanc P, Fagin B, Kulwich BA. Capillaria hepatica infection; Incidental finding in a dog with renal insufficiency. Canine practice 1983; 10: 12-14
  13. Lee CW. The experimental studies on Capillaria hepatica. Korean J Parasitol 1964; 2: 63-80 https://doi.org/10.3347/kjp.1964.2.1.63
  14. Lee SH, Eom KS, Rim HJ. Kinetics of classes of antibodies to Capillaria hepatica using indirect fluorescent antibody test during murine infection. Dept Parasitol and Instit Trop Endemic Disease, College of Med, Korea Univ 1987; 24: 97-103
  15. Liat LB, Fong YL, Krishnasamy M. Capillaria hepatica infection of wild rodents in Peninsular Malaysia. Southeast Asian J Trop Med Publ Hlth 1977; 8: 354-358
  16. Min HK. Prevalence of Capillaria hepatica among house rat in seoul. Korean J Parasitol 1979; 17: 93-97 https://doi.org/10.3347/kjp.1979.17.2.93
  17. Nation PN, Dies KH. Capillaria hepatica in a horse. Can Vet J 1978; 19: 315-316
  18. Pannenbecker J, Miller TC, Muller J, Jeschke R. Schwerer Leberbefall durch Capillaria hepatica. Monatsschr Kinderheilkunde 1990; 138: 767-771
  19. Rao RR, Marathe MR, Nair TB, Gangoli SD. Capillaria hepatica in a Mongrel dog. Indian Vet J 1975; 52: 393-394
  20. Sekikawa H, Hasegawa H, Otsuru M, Igarash T, Kaneko H, Wada K, Sato O, Wakakuwa R, Tajima K, Homma K. First human case of Capillaria hepatica infection in Japan. Jap J Parasitol 1991; 4: 528-532
  21. Seo BS, Rim HJ, Lee CW, Yoon JS. Studies on the parasitic helminths of Korea. II. Parasites of the rat, Rattus norvegicus erxl in Seoul with the description of Capillaria hepatica (Bancroft, 1893, Travassos,1915). Korean J Parasitol 1964; 2: 55-62 https://doi.org/10.3347/kjp.1964.2.1.55
  22. Seong JK, Yun YM, Han JH, Lee JS, Oh YS. Spontaneous infection of Capillaria hepatica in wild rats(Ratus norvegicus) of Korea. Korean J Vet Res 1998; 38: 600-605
  23. Shin EK, Han JH. Pathological studies on the hepatic fibrosis induced by Capillaria hepatica. Korean J Vet Res 1998; 38: 119-128
  24. Smit JD. Capillaria hepatica infestation in a dog. Onderstepoort J Vet Res 1960; 28: 473-478
  25. Stokes B. Capillaria hepatica in a dog. Australian Vet J 1973; 49: 109-110 https://doi.org/10.1111/j.1751-0813.1973.tb09338.x
  26. Wobeser G, Rock TW. Capillaria hepatica (Nematoda: Trichuridae) in a coyote. J Wildl Dis 1973; 9: 225-226