한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제21권2호
  • /
  • Pages.154-160
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  • 2004
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

황체낭종우에서 Dinoprost 또는 Fenprostalene 치료에 대한 난소 및 낭종의 반응

Response of Ovaries and Cyst According to Treatment with Dinoprost or Fenprostalene in Dairy Cows with Ovarian Luteal Cyst

  • 강현구 (충북대학교 수의과대학 및 동물의학연구소) ;
  • 김일화 (충북대학교 수의과대학 및 동물의학연구) ;
  • 백인석 (전남대학교 수의과대) ;
  • 손창호 (전남대학교 수의과대) ;
  • 이청산 (충청북도 축산위생연구소)
  • 발행 : 2004.06.01
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초록

This study was carried out to monitor the response of ovaries and cyst according to treatment with dinoprost or fenprostalene in dairy cows with ovarian luteal cyst. Twenty cows were diagnosed as luteal cysts by rectal palpation, ultrasonography and progesterone analysis. The cystic cows were treated with dinoprost or fenprostalene. All the animals were re-examined by ultrasonography and blood was collected for the measurement of plasma progesterone concentration at day 0 (the day of treatment), 3, 13 and 24, respectively. Mean plasma progesterone concentrations on day -11 and day -1 before treatment were 2.1$\pm$0.2 ng/ml and 2.8$\pm$0.3 ng/ml, respectively. On day 3 and day 13 were 0.3$\pm$0.1 ng/ml and 4.3$\pm$0.2 ng/ml, respectively. Mean cystic wall thickness on day -11 and day -1 were 3.2$\pm$0.2 mm and 3.9$\pm$0.2 mm, respectively. And on day 3 was 2.4$\pm$0.3 mm. The responses of luteal cyst after treatment noted during ultrasonography included dramatical degeneration of the luteal tissue of cystic wall on day 3 (all cows), slowly reduction of cyst size (cyst resolution) until last examination (8 cows), complete disappearance on day 13 (7 cows) and no changes of cyst size (5 cows). A group of 10 cows with luteal cysts injected fenprostalene compared with another 10 cows treated dinoprost showed a slightly higher pregnancy rate on first service after initial treatment (50.0 vs 30.0%). But treatment effects of dinoprost or fenprostalene did not significantly different results for each groups. This study suggested that the response of the cyst according to treatment revealed various types. Therefore, veterinarians should have attention on monitoring of the response of cystic ovaries after treatment, specially on no change of cyst size after treatment.

키워드

참고문헌

  1. AI-Dahash SYA, David JSE. Anatomical featu,res of cystic ovaries in cattle found during an abattoir survey. Vet Rec 1977; 101: 320-324 https://doi.org/10.1136/vr.101.16.320
  2. Blowey RW. Milk progesterone profiles in untreated cystic ovarian disease. Vet Rec 1992; 130: 429 https://doi.org/10.1136/vr.130.19.429
  3. Carroll DJ, Pierson RA, Hauser ER, Grummer RR, Combs DK: Variability of ovarian structures and plasma progesterone profiles in dairy cows with ovarian cysts. Theriogenology 1990; 34: 349-370 https://doi.org/10.1016/0093-691X(90)90528-2
  4. Cook DL, Parfet JR, Smith CA, Moss GE, Youngquist RS, Garverick HA. Secretory patterns of LH and FSH during development and hypothalamic and hypophysial characteristics following development of steroid-induced ovarian follicular cysts in dairy cattle. J Reprod Fertil1991; 91: 19-28 https://doi.org/10.1530/jrf.0.0910019
  5. Day N. The diagnosis, differentiation, and pathogenesis of cystic ovarian diseases. Vet Med 1991; 86: 753-760
  6. Farin PW, Youngquist RS, Parfet JR, Garverick HA. Diagnosis of luteal and follicular ovarian cysts by palpation per rectum and linear-array ultrasonography in dairy cows. J Am Vet Med Assoc 1992; 200: 1085-1089
  7. Farin PW, Youngquist RS, Parfet JR, Garverick HA. Diagnosis of luteal and follicular ovarian cysts in dairy cows by sector scan ultrasonography. Theriogenology 1990; 34: 633-642 https://doi.org/10.1016/0093-691X(90)90019-P
  8. Fricke PM. Scanning the future-ultrasonography as a reproductive management tool for dairy cattle. J Dairy Sci 2002; 85: 1918-1926 https://doi.org/10.3168/jds.S0022-0302(02)74268-9
  9. Gaiverick HA. Ovarian follicular cysts in dairy cows. J Dairy Sci 1991; 80: 995-1004 https://doi.org/10.3168/jds.S0022-0302(97)76025-9
  10. Guay P, Rieger D, Roberge S. Superovulatory and endocrine responses in Holstein heifers treated with either prostaglandin $F_2\alpha,$ cloprostenol or fenprostalene. Theriogenology 1988; 29: 1193-1199 https://doi.org/10.1016/S0093-691X(88)80044-X
  11. Gumen A, Wiltbank MC. An alteration in the hypothalamic action of estradiol due to lack of progesterone exposure can cause follicular cysts in cattle. Biology of Reproduction 2002; 66: 1689-1695 https://doi.org/10.1095/biolreprod66.6.1689
  12. Hackett AJ, Batra TR. The incidence of cystic ovaries in dairy cattle housed in a Total Confinement System. Canad J Comp Med 1985; 49: 55-57
  13. Hampton JH, Salfen BE, Bader JF, Keisler DH, Garverick HA. Ovarian follicular responses to high doses of pulsatile luteinizing hormone in lactating dairy cattle. J Dairy Sci 2003; 86: 1963-9 https://doi.org/10.3168/jds.S0022-0302(03)73784-9
  14. Hooijer GA, Lubbers RBF, Ducro BJ, van Arendonk JAM, Kaal-Lansbergen LMTE, van der Lende T Genetic parameters for cystic ovarian disease in Dutch black and white dairy cattle. J Dairy Sci 2001; 84: 286-291 https://doi.org/10.3168/jds.S0022-0302(01)74478-5
  15. Ijaz A, Fahning ML, Zemjanis R. Treatment and control of cystic ovarian disease in dairy cattle: A review. Br Vet J 1987; 143: 226-273 https://doi.org/10.1016/0007-1935(87)90085-6
  16. Jackson PS, Jessup R. Secondary pharmacological properties of prostaglandin. Vet Rec 1984; 114: 168
  17. Jeffcoate lA, Ayliffe TR. An ultrasonographic study of bovine cystic ovarian disease and its treatment. Vet Rec 1995; 132: 406-410
  18. Karg H, Claus R, Gunzler O, Rattenberger E, Hahn R, Hocke P. Milk progesterone assay for assessing cyclicity and ovarian dysfunction in cattle. Proc 9th Int Cong Anim Reprod & AI 1980; 2: 119-124
  19. Kesler DJ, Garverick HA. Ovarian cysts in dairy cattle: a review. J AnimSci 1982; 55: 1147-1159
  20. Kesler DJ. Therapeutic uses of gonadotropin-releasing hormone. Dompend Contin Educ Prac Vet 1997; 16: 1-9
  21. Lawson LG, Bruun J, Coelli T, Agger JF, Lund M. Relationships of efficiency to reproductive disorders in Danish milk production: a stochastic frontier analysis. J Dairy Sci. 2004; 87: 212-24 https://doi.org/10.3168/jds.S0022-0302(04)73160-4
  22. Leidl W, Stolla R, Hundschell CH, Bostedt H. Zur Ovarialzyste des Rindes. I. Klassifizierung und diagnose. Berl Munch Tierrarztl 1979; 92: 369-376
  23. Lopez-Gatius F, Lopez-Bejar M. Reproductive performance of dairy cows with ovarian cysts after different GnRH and cloprostenol treatments. Theriogenology 2002; 58: 1337-48 https://doi.org/10.1016/S0093-691X(02)00952-4
  24. Nakao T, Harada A, Kimura M, Takagi H, Kaneko K, Sugiyama S, Saito A, Moriyoshi M, Kawata K. Effect of fenprostalene 14 days after fertirelin treatment on intervals from treatment to conception in cows with follicular cysts diagnosed by milk progesterone test. J Vet Med Sci 1993; 55: 207-210 https://doi.org/10.1292/jvms.55.207
  25. Nanda AS, Ward WR, Dobson H. Lack of LH response to oestradiol treatment in cows with cystic ovarian disease and effect of progesterone treatment or manual rupture. Res Vet Sci 1991; 51: 180-184 https://doi.org/10.1016/0034-5288(91)90011-C
  26. Noble KM, Tebble JE, Harvey D, Dobson H. Ultrasonography and hormone profiles of persistent ovarian follicles (cysts) induced with low doses of progesterone in cattle. J Reprod Fertil 2000; 120: 361-366 https://doi.org/10.1530/reprod/120.2.361
  27. Peters AR. Changes in electrical resistance of the vaginal mucosa in prostaglandin-treated cows. Vet Rec 1989; 124: 505-507 https://doi.org/10.1136/vr.124.19.505
  28. Ribadu AY, Dobson H, Ward WR. Ultrasound and progesterone monitoring of ovarian follicular cysts in cows treated with GnRH. Br Vet J 1994; 150: 489-497 https://doi.org/10.1016/S0007-1935(05)80202-7
  29. Ribadu AY, Ward WR, Dobson H. Comparative evaluation of ovarian structures in cattle by palpation per rectum, ultrasonography and plasma progesterone concentration. Vet Rec 1994; 135: 452-457 https://doi.org/10.1136/vr.135.19.452
  30. Roberge S, Brown JL, Reeves JJ. Elevated inhibin concentration in the follicular fluid of dairy cows with chronic cystic ovarian disease. Theriogenology 1993; 40: 809-818 https://doi.org/10.1016/0093-691X(93)90216-R
  31. Roberts SJ. Cystic ovaries or nymphomania. In: Veterinary obstetrics and genital diseases (Theriogenology), 3rd ed. New York: Edward Brothers Inc. 1986: 478-494
  32. Seguin BE. Prostaglandin theraphy in cattle with unobserved estrus. In: Morrow DA. Current therapy in theriogenology, 1st ed. Philadelphia: WB Saunders Co. 1980: 296-299
  33. Smith RD. Estrus detection. In: Morrow DA, ed. Current theraphy in theriogeno1ogy 2, 2nd ed. Philadelphia: WB Saunders Co. 153-162, 1986
  34. Tebble JE, O'Donnell MJ, Dobson H. Ultrasound diagnosis and treatment outcome of cystic ovaries in cattle. Vet Rec 2001; 148: 411-413 https://doi.org/10.1136/vr.148.13.411
  35. Tolison RV, Spires HR, Bowen JL. Absorption and elimination of a prostaglandin $F_2\alpha$ analog, fenprostalene, in lactating dairy cows. J Dairy Sci 1985; 68: 2072-2077 https://doi.org/10.3168/jds.S0022-0302(85)81069-9
  36. Twagiramungu H, Guilbault LA, Proulx J, Villeneuves P, Dufour JJ. Influence of an agonist of gonadotropin-releasing hormone (Buserelin) on estrus synchronization and fertility in beef cows. J Anim Sci 1992; 70: 1904-1910
  37. Wiltbank MC, Gtirnen A, Sartori R. Physiological classification of nonovulatory conditions in cattle. Theriogenology 2002; 57: 21-52 https://doi.org/10.1016/S0093-691X(01)00656-2
  38. $\phi$Tergaard S, Grohn YT. Effects of diseases on test day milk yield and body weight of dairy cows from Danish research herds. J Dairy Sci 1999; 82:1188-1201 https://doi.org/10.3168/jds.S0022-0302(99)75342-7
  39. 康炳奎, 崔漢善, 鄭永基. 韓牛 및 乳牛의 卵巢囊腫에 관한 解剖組織學的所見 및 난소 hormone 分析. 大韓獸醫學會誌 1987; 27: 141-151
  40. 손창호, 강병규, 최한선, 강현구, 오기석, 서동호, 석국현. ㅡ초음파검사에 의한 소의 번식장애 감별진단 및 치료법의 개발. II. 무발정우의 감별진단. 한국임상수의학회지 1998; 15: 307-318