KIEE International Transactions on Electrophysics and Applications

대한전기학회 (The Korean Institute of Electrical Engineers)
권호 표지

Indicator-free DNA Chip Array Using an Electrochemical System

  • Park, Yong-Sung (School of Electrical, Electronic and Information Engineering, Wonkwang University) ;
  • Kwon, Young-Soo (Div. of Electrical, Electronic and Computer Eng., Dong-A University) ;
  • Park, Dae-Hee (School of Electrical, Electronic and Information Engineering, Wonkwang University)
  • 발행 : 2004.08.01
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초록

This research aims to develop a DNA chip array without an indicator. We fabricated a microelectrode array through photolithography technology. Several DNA probes were immobilized on an electrode. Then, target DNA was hybridized and measured electrochemically. Cyclic-voltammograms (CVs) showed a difference between the DNA probe and mismatched DNA in an anodic peak. This indicator-free DNA chip resulted in a sequence-specific detection of the target DNA.

키워드

참고문헌

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