대한화장품학회지 (Journal of the Society of Cosmetic Scientists of Korea)

  • 제30권1호
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  • Pages.39-51
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  • 2004
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  • 1226-2587(pISSN)
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  • 2288-9507(eISSN)
대한화장품학회 (Society of Cosmetic Scientists of Korea)
권호 표지

오존에 의한 피부손상 확인 및 이를 방어하는 피부 외용제 소재의 탐색

Identification of Ozone-induced Skin Damage and Screening of Antioxidant for Ozone

  • 발행 : 2004.05.01
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초록

Ozone(O$_3$), one of best-known toxic air pollutant, act as a strong oxidant. It is possible that skins exposed to the air can be easily damaged by such oxidative air pollutants. Therefore, in the present study, anti-oxidative effects of natural product. on $O_2$ㆍ and ㆍOH were investigated by EPR. Ozone caused protein damage and lipid oxidation, in HaCaT and B16F10 leading ultimately to programmed cell death. It also reduced the level of antioxidant molecules including ascorbic acid and tocopherol in stratum comeum. However, antioxidants originated from natural products could protect skin from these products could protect skin from these oxidative damages. We concluded that eight natural extracts including Rosa davurica, Ligularia sibrica, Green tea acted as strong antioxidants against ozone.

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참고문헌

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