Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Effects of Ligands on the Allosteric Property of Tryptophan Synthase

트립토판 합성효소의 이소조절성에 미치는 리간드

  • Kim, Il (Department of Molecular Biology, College of Natural Sciences, Pusan National University) ;
  • Shin, Hye-Ja (Environmental Engineering Major, Division of Applied Engineering, Dongseo University) ;
  • Im, Woon-Ki (Department of Molecular Biology, College of Natural Sciences, Pusan National University) ;
  • Kim, Han-Do (Department of Molecular Biology, College of Natural Sciences, Pusan National University)
  • 김일 (부산대학교 자연과학대학 분자생물학과) ;
  • 신혜자 (동서대학교 응용공학부 환경공학전공) ;
  • 임운기 (부산대학교 자연과학대학 분자생물학과) ;
  • 김한도 (부산대학교 자연과학대학 분자생물학과)
  • Published : 2004.02.01
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Abstract

Various ligands function as regulators in the allosteric control of tryptophan synthase. Effects of the monovalent cations and glycerophosphate on the mutant tryptophan synthases were examined in the presence of L-serine. The results showed that these compounds might play roles in the allosteric control of the proteins.

트립토판 합성효소의 이소조절성에 작용하는 리간드가 알려져 있다. $\beta$반응의 기질인 세린만이 있는 조건에서 일가 양이온과 glycerophosphate의 리간드효과를 잔기치환체를 사용하여 조사하였다. 이들 리간드가 이 효소의 이소조절성에 관여하고 있음을 보여주고 있다.

Keywords

References

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