수삼의 지역별 연근별 인삼사포닌 함량 비교

Comparison of Ginsenoside Composition and Contents in Fresh Ginseng Roots Cultivated in Korea, Japan, and China at Various Ages

  • 이충렬 (중앙대학교 인삼산업연구센터) ;
  • 황완균 (중앙대학교 약학대학) ;
  • 신차균 (중앙대학교 생명공학과) ;
  • 이학성 (중앙대학교 생명공학과) ;
  • 한성태 (중앙대학교 생명공학과) ;
  • 임병옥 (중앙대학교 인삼산업연구센터) ;
  • 고성권 (중앙대학교 인삼산업연구센터)
  • 발행 : 2004.10.31

초록

한국산 6개 지역(금산, 강화, 풍기, 음성, 진안, 홍천) 수삼의 ginsenoside 함량을 비교 분석하여 평균 및 분산분석(일원배치법)을 통계 처리한 결과, 함량의 평균치가 4년근 수삼이 가장 높은 함유량을 나타내었고, 다음으로 5년근, 6년근 순 이었으나, 인삼사포닌에 대한 연근별 차이에 있어서 통계적 처리에 의한 유의적 차이는 없었다. 동북아시아의 또 다른 인삼 재배지인 중국 길림성과 일본의 나가노산 수삼과의 ginsenoside 함량에 있어서는 한국 금산산 수삼이 중국 길림성산 및 일본산에 비하여 높은 함유량을 나타내었다.

Cooking basic information for indexing of fresh ginseng roots (Panax ginseng C. A. Meyer) was determined. Ginsenoside contents of various age fresh ginseng roots cultivated in Northeast Asia were quantitatively analyzed by HPLC. Average contents of total saponin and each ginsenoside of 4-year-old fresh ginseng root cultivated in Korea were higher than those cultivated fur longer periods (5- and 6-year-old). One-way analysis variance showed average contents of total saponin and each ginsenoside of 4-, 5-, and 6-year-old fresh ginseng roots were not statistically significant. Four-year-old fresh ginseng root cultivated at Geumsan, Korea contained the highest ginsenoside content among samples studied.

키워드

참고문헌

  1. Chung HB, Lee CB, Yoon SW, Lee JH, Choi S, Ko SK, Park H, Lim BO. Strategies of Globalization for Ginseng Industry. Ijin Publishing, Seoul, Korea (2003)
  2. Namba T. The Encyclopedia of Wakan-Yaku with Color Pictures. Hoikusha, Osaka, Japan (1980)
  3. Sanata S, Kondo N, Shoji J, Tanaka O, Shibata S. Studies on the saponins of ginseng. I. Structure of ginsenoside-R$_0, Rb_1, Rb_2,$ Rc and Rd. Chem. Pharm. Bull. 22: 421-428 (1974) https://doi.org/10.1248/cpb.22.421
  4. Yokozawa T, Kobayashi T, Oura H, Kawashima Y. Studies on the mechanism of the hypoglycemic activity of ginsenoside-Rb$_2$ in streptozotocin-diabetic rats. Chem. Pharm. Bull. 33: 869-872 (1985) https://doi.org/10.1248/cpb.33.869
  5. Mochizuki M, Yoo YC, Matsuzawa K, Sato K, Saiki I, Tonooka S, Samukawa K, Azuma I. Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside-Rb2, 20(R)- and 20(S)-ginsenoside- Rg$_3$, of red ginseng. Biol. Pharm. Bull. 18: 1197-1202 (1995) https://doi.org/10.1248/bpb.18.1197
  6. Jeong CS, Hyun JE, Kim YS. Anti-oxidative effect of ginsenoside $Rb_1$ on the HC1 . ethanol-induced gastric tissue in rats. Korean J. Pharmacogn. 33: 252-256 (2002)
  7. Jung IS, Cho YD. Effect of ginseng saponin fraction on absorption of cholesterol and serum lipid components. Korean J. Ginseng Ginseng Sci. 9: 232-239 (1985)
  8. Yoon SH, Joo CN. Study on the preventive effect of ginsenosides against hypercholesterolemia and its mechanism. Korean J. Ginseng Sci. 17: 1-12 (1993)
  9. Matsuda H, Samukawa K, Kubo M. Anti-hepatitic activity of ginsenoside Ro. Planta Med. 57: 523-526 (1991) https://doi.org/10.1055/s-2006-960198
  10. Wang BX, Cui JC, Liu AJ, Wu SK. Studies on the anti-fatigue effect of the saponins of stems and leaves of Panax ginseng (SSLG). J. Tradit. Chin. Med. 3: 89-94 (1983)
  11. Saito H, Yoshida Y, Tagaki K. Effects of Panax ginseng root on exhaustive exercise in mice. Jpn J. Pharmacol. 24: 119-126 (1974) https://doi.org/10.1254/jjp.24.119
  12. Matsuda H, Samukawa K, Kubo M. Anti-inflammatory activity of ginsenoside Ro. Planta Medica. 56: 19-23 (1990) https://doi.org/10.1055/s-2006-960875
  13. Park JD. Recent studies on the chemical constituents of Korean Ginseng (Panax ginseng C.A. Meyer). Korean J. Ginseng Sci. 20: 389-415 (1996)
  14. Jang JG, Lee KS, Kwon DW, Nam KY, Choi JH. Study on the changes of saponin contents in relation to root age of Panax ginseng. Korean J. Food Nutr. 12: 37-40 (1983)
  15. Namba T, Yoshizaki M, Tomimori T, Kobashi K, Mitsui K. Chemical and biochemical evaluation of ginseng and related crude drugs. Yakugaku Zasshi. 94: 252-260 (1974) https://doi.org/10.1248/yakushi1947.94.2_252
  16. Ko SR, Choi KJ, Kim SC, Han KW. Content and composition of saponin compounds of Panax species. Korean J. Ginseng Sci. 19: 254-259 (1995)
  17. Kim MW, Ko SR, Choi KJ, Kim SC. Distribution of saponin in various sections of Panax ginseng root and changes of its contents according to root age. Korean J. Ginseng Sci. 11: 10-16 (1987)
  18. Shibata S, Tanaka T, Ando T, Sado M, Tsushima S, Ohsawa T. Chemical studies on oriental plant drugs (XIV). Protopanaxadiol, a genuine sapogenin of ginseng saponins. Chem. Pharm. Bull. 14: 595-600 (1966) https://doi.org/10.1248/cpb.14.595
  19. Ko SK, Lee CR, Choi YE, Im BO, Sung JH, Yoon KR. Analysis of ginsenosides of white and red ginseng concentrates. Korean J. Food Sci. Technol. 35: 536-539 (2003)