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A Clinical Study on the Effects of Intravenous Wild ginseng Herbal Acupuncture on the Human Body

정맥 주입용 산삼약침이 인체에 미치는 영향에 관한 임상적 연구

  • Kwon, Ki-Rok (Department of Acupuncture and Moxibustion, SangJi Oriental Medicine Hospital, SangJi University)
  • 권기록 (상지대학교 한의과대학 침구과)
  • Published : 2004.02.29

Abstract

Background : This study was conducted to evaluate the effects of wild ginseng herbal acupuncture developed for the intravenous use. Healthy male and female volunteers(n=57) went through Randomized Control Trials(RCT). Methods : For those who are under a medication due to common cold or other illnesses were excluded in the primary stage and the subjects with possible abnormalities in the pre-screening process were also excluded in the secondary stage. Then the examination groups were determined by random sampling. Experiment groups were divided into Normal saline injection group(control group), cultivated wild ginseng herbal acupuncture group(experiment group 1) and natural wild ginseng herbal acupuncture group(experiment group 2) Blood tension, body temperature, pulse, and other criteria were measured and analyzed. Results : 1. Intravenous injection of cultivated wild ginseng herbal acupuncture and natural wild ginseng herbal acupuncture didn't cause significant changes in the blood tension, pulse, body temperature, and etc. 2. No significant differences were witnessed in CBC, ESR, biochemistry of blood test and UA between the experiment groups. 3. No significant changes were noted in the thermography before and after the test in the experiment groups. 4. Some of the common physical changes occurring during and after the administration were fatigue, chest distension, and headache in all of the experiment groups. 5. Comparing general condition after one week from the termination of administration, the control group showed worst condition while as the natural wild ginseng herbal acupuncture group displayed best condition. Conclusion : From the above results, we can carefully deduce that the intravenous injection of the wild ginseng herbal acupuncture didn't show significant differences compared to injection of the normal saline. We can infer it is safe on the human body and further studies and reports must be followed.

Keywords

References

  1. 신순식 외, 산삼 감정 기준의 객관성. 한의학연구소 동의 한의연 제5집, pp.107-114.2001.12.
  2. 전국한의과대학 본초학교수공편저, 본초학, 서울, 영림사. p. 531, 1994.
  3. 중약대사전편찬위원회. 완역중약대사전 권7. 서울, 정담, pp. 3473-3479, 1997.
  4. 朝鮮總督府專賣局. 人蔘史. 서울, 法人文化社. pp.3-4, p.5.
  5. 張仲景. 仲景全書, 대성문화사, p. 130, 150, 153, 155, 166, 167, 176, 199, 201, 205, 208, 209, 214, 217, 1984.
  6. 권기록 외, 山蔘에 대한 文獻的 考察. 대한약침학회지, Vol. 6, No.2, p. 75, 2003. https://doi.org/10.3831/KPI.2003.6.2.067
  7. 이상인 외, 한약임상응용. 성보사, pp. 345-350, 1982.
  8. 하대유. 인삼에 대한 세포학 및 면역학적 연구. 대한 면역학회지 Vol. 1, No. 1, pp. 45-52, 1979.
  9. 山田昌之. 朝鮮人蔘의 硏究. 日本藥理學會誌 51 : 390, 1955.
  10. Brekhman I.I. Panax ginseng, Gosudarst Isdat et Med. Lit. Leningard p.1 1957.
  11. Garriques S. Panax Quinquefolia. Am Chem Pharm 90: 331, 1954.
  12. 최진호. 인삼의 신비. 서울: 교문사, pp.13-14, 1984.
  13. Takagi K. , Proceedings International Ginseng Symposium, The Central Research Institute, Office of Monopoly, Seoul, Korea p. 119, 1974.
  14. 대한약침학회. 약침요법 시술 지침서. 대한약침학회, 서울, pp. 13-14, 112-118, 138-203, 1999.
  15. 손인철 외, 약침요법. 일중사. p. 17, 18. 1999.
  16. 이산명 외, 인삼, 녹용 및 목향 수침이 흰쥐의 체중 및 소화관 호르몬 분비에 미치는 영향. 대한침구학회지, Vol. 5, No.1, pp. 1-5, 1988.
  17. 김웅시 외, 수삼, 백삼 및 홍삼수침이 Alloxan 당뇨병 흰쥐에 미치는 영향. 대한 침구학회지, Vol. 6, No.1, pp. 1-5, 1989.
  18. 남윤석, 약침용 홍삼추출액의 안전성 연구. 경희대학교 대학원, 1996.
  19. 권기록 외, 정맥주입용 산양산삼 증류약침의 급성.아급성 독성 실험 및 Sarcoma-180 항암 효과에 관한 실험적 연구, 대한약침학회지, Vol. 6, No.2, pp. 7-27, 2003. https://doi.org/10.3831/KPI.2003.6.2.007
  20. 楊甲三, 鍼灸學. 北京, 인민위생출판사, p. 213, 367. 1989.
  21. 전국한의과대학 침구경혈학 교실, 鍼灸學(上), p.323, 667, 2000.
  22. 강성길 외, 인삼수침이 진통 및 혈압에 미치는 영향, 동양의학학회지, Vol. 11 , No.2, pp. 66-75, 1985.
  23. 김태윤 외, 인삼수침전처리가 발암예방에 미치는 영향, 대한한의학회지, Vol. 9, No.2, pp. 33-44, 1988.
  24. 황경애 외, 인삼 및 녹용수침의 시간경과에 따른 면역효과연구, 경희의학, Vol. 4, No.2, pp.150-157, 1988.
  25. 이혜정 외, 강혈당작용에 의거한 종류별 인삼수침엑기스 제법연구. 대한한의학회지, Vol. 13,No.1, pp.23-40, 1992.
  26. 김용석 외, 인삼수침이 흰쥐의 갑상선 기능저하에 미치는 영향, 경희의학, Vol. 6, No.2, pp. 202-210, 1990.
  27. 임하변 외, 인삼수침이 항 알레르기에 미치는 영향. 경희의학, Vol. 7, No.1, pp. 63-72, 1991.
  28. 김창일 외, 농도별 인삼수침이 hydrocortisone acetate를 투여한 흰쥐의 체내대사에 미치는 영향. 대한한의학회지, Vol. 9, No.2, pp. 33-44, 1988.
  29. 金一勳. 神藥. 나무출판사, pp. 51-53, 1986.
  30. Major R.H., 임상진단학. 계축문화사, pp. 326-329. 1988.
  31. 의학교육연수원, 가정의학, 서울대학교 출판부, p.85, 846, 1987.
  32. 이귀녕, 이종순, 임상병리파일, 의학문화사, pp. 8496, p. 106, 150, 229, 256, pp. 664-672, 735-740, p. 767, 770. 1996.
  33. Fischer AA. Documentation of myofascial trigger points. Arch Phys med Rehabil 96, p. 286, 1988.
  34. 홍원식. 精校 黃帝內經素問, 東洋醫學硏究院 出版社, p. 34, 35. 1985.
  35. 楊維傑 編, 黃帝內經靈樞譯解, 성보출판사, p.489, 1985.

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