Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • 제30권3호
  • /
  • Pages.228-233
  • /
  • 2004
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  • 2234-7550(pISSN)
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  • 2234-5930(eISSN)
대한구강악안면외과학회 (The Korean Association of Oral and Maxillofacial Surgeons)
권호 표지

구개골에 발생한 악성 Peripheral Nerve Sheath Tumor의 증례보고

MALIGNANT PERIPHERAL NERVE SHEATH TUMOR ON PALATE: A CASE REPORT

  • 권민수 (전북대학교 치과대학 구강악안면외과학교실, 구강생체과학연구소) ;
  • 이현상 (전북대학교 치과대학 구강악안면외과학교실, 구강생체과학연구소) ;
  • 김현창 (전북대학교 치과대학 구강악안면외과학교실, 구강생체과학연구소) ;
  • 고승오 (전북대학교 치과대학 구강악안면외과학교실, 구강생체과학연구소) ;
  • 신효근 (전북대학교 치과대학 구강악안면외과학교실, 구강생체과학연구소)
  • Kwon, Min-Su (Department of Oral & Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University) ;
  • Lee, Hyun-Sang (Department of Oral & Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University) ;
  • Kim, Hyun-Chang (Department of Oral & Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University) ;
  • Ko, Seung-O (Department of Oral & Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University) ;
  • Shin, Hyo-Keun (Department of Oral & Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University)
  • 발행 : 2004.06.30
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초록

Summary: The malignant peripheral nerve sheath tumor(MPNST) is an aggressive neoplasm and can either arise independently or result from malignant change in preexisting neurofibromatosis (von Recklinghausen's disease). Its histologic characteristics remain controversial, but currently it is believed that the schwann cell is the origin of the peripheral nerve sheath tumors. MPNST is an uncommon neoplasm of the head and neck region, and its presentation in the oral cavity is quite rare. In this study, we report a patient with a rare case of a MPNST involving the maxilla. A case report: A 29-year-old female presented with a chief complaint of painless swelling with bleeding tendency on the left maxillary tuberosity area 2 months ago. Clinical examination showed a $5.0{\times}3.0cm^2$ sized, indurative swelling on the site. Conventional radiographs showed a relatively well-defined soft tissue mass involving the left maxillary sinus, and destruction of the anterior, posterolateral walls of the left maxillary sinus. Subtotal maxillectomy and split-thickness skin graft from thigh were undertaken. In histochemical and immunohistochemical studies, the specimen revealed positive reactivities to Vimentin and S-100 protein. Final diagnosis was made as MPNST.

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참고문헌

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