생약학회지 (Korean Journal of Pharmacognosy)

한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

보골지와 염초보골지의 Psoralen과 Angelicin 함량 분석

Quantitative Analysis of Psoralen and Angelicin in the Psoraleae Semen and Processed Psoraleae Semen

  • 이혜원 (한국한의학연구원 검사사업부) ;
  • 천진미 (한국한의학연구원 검사사업부) ;
  • 이아영 (한국한의학연구원 검사사업부) ;
  • 고병섭 (한국한의학연구원 한약제제연구부) ;
  • 김호경 (한국한의학연구원 검사사업부)
  • Lee, Hye-Won (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine) ;
  • Chun, Jin-Mi (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine) ;
  • Lee, A-Yeong (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine) ;
  • Ko, Byoung-Seob (Department of Herbal Research, Korea Institute of Oriental Medicine) ;
  • Kim, Ho-Kyoung (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
  • 발행 : 2004.09.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Psoralen is used in the treatment of vitiligo and angelicin(isopsoralen) is a photosensitizing agent. A reversed-phase high performance chromatographic method was developed to determine the contents of psoralen and angelicin from Psoraleae Semen and processed Psoraleae Semen. The contents of psoralen and angelicin from Psoraleae Semen showed 0.39% and 0.34% respectively. Processing Psoraleae Semen showed that increased the contents of psoralen (0.52%) and angelicin (0.50%).

키워드

참고문헌

  1. 한국의약품수출입협회(2003) 한약재감별주해, 248-250. 도서출판 대영, 서울
  2. 식품의약품안전청(2002) 대한약전외한약(생약)규격집, 177. 동원출판사, 서울
  3. 신문농출판공가(1995)중약대사전, 2782. 일중사, 서울
  4. 王浴生(1983) 中藥藥理與應用, 547-550. 人民衛生出版 社, 北京
  5. 김재길(1992) 임상응용 한약포제학, 275-278. 약업신문사, 서울
  6. 육창수, 남수영, 예재호, 유기욱, 김형근(1992) 한약학II, 660-661. 광명의학사, 서울
  7. 中華人民共和國衛生部藥典委員會(1985) 中準人民共和國 藥典 1部, 154. 人民衛生出版社,北京
  8. 新文風出版公司(1982) 新編中藥大辭典(下), 2068-2070. 新文風出版公司, 臺北
  9. 中國醫學科學院藥物硏究所(1984) 中藥志(第3冊), 429-435. 人民衛生出版, 北京
  10. 전국한의과대학 본초학 교수 공동저(1991) 本草學, 559-560. 영림사, 서울
  11. Nguyen Thanh Dong, Ki Hwan Bae, Young Ho Kim, Gwi Seo Hwang, Ok Soon Hwang, Se Eun Kim, and Jong Seong Kang (2003) Quandtative determination of psoralen and angelicin from some medicinal herbs by high performanceliquid chromatography. Arch. Pharm. Res. 26(7): 516-520 https://doi.org/10.1007/BF02976873
  12. Yang, B., Yao, S., and Cui, S. (1996) Comparison of ancient and modern processing methods for fructus Psoraleae, Zhongguo Zhong Yao Za Zhi. 21(9): 537-539
  13. Tan, S., Wang, Y, Liu, G., Guo, D., and Han, J. (1995) Determination of psoralen and isopsoralen in tincture of fructus Psoraleae by HPLC. Zhongguo Zhong Yao Za Zhi. 20(2): 99-100
  14. 김호철(2001) 한약재 수치법제의 규격화 연구, 374-379. 보건복지부, 서울
  15. 식품의약품안전청(2002) 대한약전 제 8개정, 1654-1655. (주)약업신문, 서울