Quantitative Analysis of Psoralen and Angelicin in the Psoraleae Semen and Processed Psoraleae Semen

보골지와 염초보골지의 Psoralen과 Angelicin 함량 분석

  • Lee, Hye-Won (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine) ;
  • Chun, Jin-Mi (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine) ;
  • Lee, A-Yeong (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine) ;
  • Ko, Byoung-Seob (Department of Herbal Research, Korea Institute of Oriental Medicine) ;
  • Kim, Ho-Kyoung (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
  • 이혜원 (한국한의학연구원 검사사업부) ;
  • 천진미 (한국한의학연구원 검사사업부) ;
  • 이아영 (한국한의학연구원 검사사업부) ;
  • 고병섭 (한국한의학연구원 한약제제연구부) ;
  • 김호경 (한국한의학연구원 검사사업부)
  • Published : 2004.09.30

Abstract

Psoralen is used in the treatment of vitiligo and angelicin(isopsoralen) is a photosensitizing agent. A reversed-phase high performance chromatographic method was developed to determine the contents of psoralen and angelicin from Psoraleae Semen and processed Psoraleae Semen. The contents of psoralen and angelicin from Psoraleae Semen showed 0.39% and 0.34% respectively. Processing Psoraleae Semen showed that increased the contents of psoralen (0.52%) and angelicin (0.50%).

Keywords

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