Chemical Constituents and Biological Activities of Cichorium intybus L.

  • El-Lakany, Abdalla M. (Pharmacognosy Department, Faculty of Pharmacy, University of Alexandria) ;
  • Aboul-Ela, Maha A. (Pharmacognosy Department, Faculty of Pharmacy, University of Alexandria) ;
  • Abdul-Ghani, Mohamed M. (Department of Organic Chemistry, Faculty of Science, Beirut Arab University) ;
  • Mekky, Hattem (Pharmacognosy Department, Faculty of Pharmacy, University of Alexandria)
  • 발행 : 2004.04.30

초록

Continuation of a phytochemical study of Cichorium intybus L. (Astraceae) growing in Egypt, resulted in the isolation and identification of a new sesquiterpene lactone 3,4-dihydrolactucin, in addition to the eight known compounds; kaempferol, isoscutellarin, cichoriin, umbelliferone, lupeol, lupeol acetate, ${\beta}-sitosterol$, and ${\beta}-sitosterol-3-O-glucoside$. Chemical structures of the isolated compounds were assigned based on different physical, chemical, and spectroscopic techniques including IR, UV, MS, 1D- and 2D-NMR spectra. Furthermore, the antimicrobial, and spasmogenic activities of some fractions and isolates were also assessed.

키워드

참고문헌

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