Journal of Korean Medicine for Obesity Research (한방비만학회지)

The Society of Korean Medicine for obesity Research (한방비만학회)
권호 표지

Effect of Ephedra Sinica and Evodia Rutaecarpa on Resting Metabolic Rate in Obese Premenopausal Women during Low-calorie Diet: A Randomized Controlled Clinical Trial

저열량 식이요법을 한 폐경 전 비만 여성의 휴식 대사량에 대한 마황과 오수유의 효과

  • Kim, Su-Jin (Department of Oriental Rehabilitation Medicine, College of Medicine, Pochon CHA University) ;
  • Ko, Byung-Pyo (Department of Oriental Rehabilitation Medicine, College of Medicine, Pochon CHA University) ;
  • Kim, Hyung-Do (Department of Oriental Internal Medicine, College of Medicine, Pochon CHA University) ;
  • Kim, Jin-Ah (Department of Oriental Internal Medicine, College of Medicine, Pochon CHA University) ;
  • Park, Jeong-Mi (Department of Oriental Internal Medicine, College of Medicine, Pochon CHA University) ;
  • Choi, Seung-Ki (Department of Pharmacology, College of Medicine, Pochon CHA University) ;
  • Jeon, Uoo-Hyun (Saeng-Hwal-Mi Oriental Medicine Clinic) ;
  • Kim, Ho-Jun (Department of Oriental Rehabilitation Medicine, College of Medicine, Pochon CHA University)
  • 김수진 (포천중문의과대학 분당차 한방병원 한방 재활의학과 교실) ;
  • 고병표 (포천중문의과대학 분당차 한방병원 한방 재활의학과 교실) ;
  • 김형도 (포천중문의과대학 분당차 한방병원 한방 내과 교실) ;
  • 김진아 (포천중문의과대학 분당차 한방병원 한방 내과 교실) ;
  • 박정미 (포천중문의과대학 분당차 한방병원 한방 내과 교실) ;
  • 최승기 (포천중문의과대학 분당차 병원 약제과) ;
  • 전우현 (생활미 한의원) ;
  • 김호준 (포천중문의과대학 분당차 한방병원 한방 재활의학과 교실)
  • Published : 2004.12.03
Download PDF
⟨ Previous Next ⟩

Abstract

Objective: To evaluate the effect of Ephedra Sinica and Evodia Rutaecarpa on resting metabolic rate(RMR), weight and body composition in obese women during low-calorie diet. Methods: We recruited 90 healthy premenopausal women$(body\;mass\;index{\geq}25kg/m^2)$ and randomly assigned to three groups(ephedra group, evodia group and placebo group). Subjects were administered Ephedra Sinica(6g twice a day) or Evodia Rutaecarpa(6g twice a day) or placebo in a double-blind fashion and participated in low-calorie diet for 8 weeks. Resting metabolic rate and body composition were measured at baseline, 4 and 8 weeks. Results: RMR change for 4 weeks was significantly higher in the ephedra group compared with the placebo group(p<.05). But the change for 8 weeks was not significant and the Evodia group showed no significant RMR change. Weight and percent body fat changes for 4 weeks and 8 weeks were significantly higher than the placebo group in the ephedra group(p<.05), but the Evodia group didn't show significant level. Conclusions: This study supports and emphasizes the benefits of herbal medicine in maintaining or increasing RMR during low-calorie diet. Especially Ephedra treatment was effective on significant maintainment of RMR, loss of weight and percent body fat(P<.05).

Keywords