대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제25권4호
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- Pages.93-104
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- 2004
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- 1226-9174(pISSN)
맥문동(麥門冬)이 C57BL/6J 생쥐의 Bleomycin 폐섬유화(肺纖維化)에 미치는 영향(影響)
The Inhibitory Effects of Liriopis Tuber on the Bleomycin-induced lung fibrosis in C57BL/6J mice
- 이형구 (경희대학교 한의과대학 폐계내과교실) ;
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정승기
(경희대학교 한의과대학 폐계내과교실) ;
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정희재
(경희대학교 한의과대학 폐계내과교실) ;
- 이병삼 (경희대학교 한의과대학 폐계내과교실)
- Rhee, Hyung-Koo (Division of Respiratory System, Department of Internal Medicine, College of Oriental Medicine, Kyunghee University) ;
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Jung, Sung-Ki
(Division of Respiratory System, Department of Internal Medicine, College of Oriental Medicine, Kyunghee University) ;
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Jung, Hee-Jae
(Division of Respiratory System, Department of Internal Medicine, College of Oriental Medicine, Kyunghee University) ;
- Lee, Byeong-Sam (Division of Respiratory System, Department of Internal Medicine, College of Oriental Medicine, Kyunghee University)
- 발행 : 2004.12.30
초록
Objectives : The aim was to identify the inhibitory effects of Liriopis Tuber on bleomycin-induced lung fibrosis by analysing the changes of imflammatory cell cytokines and SHI(Semiquantitative Histological Index), Materials and Methods : In this study fibrosis prone C57BL/6J mice were used. Control group was treated with blomycin(0.06mg/0.1 ml) by IT(intratracheal) instillation which is a popular method of inducing lung fibrosis and sample group took Liriopis Tuber water extract(38.0mg/10g body weight) orally for 14 days after IT instillation of blomycin. We measured the total and differential count of WBC,