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Fabrication and Characteristics of MOSFET Protein Sensor Using Nano SAMs

자기조립 단분자막을 이용한 MOSFET형 단백질 센서의 제작 및 특성

  • Han, Seung-Woo (Department of Electronics, Kyungpook National University) ;
  • Park, Keun-Yong (Department of Electronics, Kyungpook National University) ;
  • Kim, Min-Suk (Department of Electronics, Kyungpook National University) ;
  • Kim, Hong-Seok (Department of Industrial Chemistry, Kyungpook National University) ;
  • Bae, Young-Seuk (Department of Biochemistry, Kyungpook National University) ;
  • Choi, Sie-Young (Department of Electronics, Kyungpook National University)
  • Published : 2004.03.31

Abstract

Protein and gene detection have been growing importance in medical diagnostics. Field effect transistor (FET) - type biosensors have many advantages such as miniaturization, standardization, and mass-production. In this work, we have fabricated metal-oxide-semiconductor (MOS) FET that operates as molecular recognitions based electronic sensor. Measurements were taken with the devices under phosphate buffered saline solution. The drain current ($I_{D}$) was decreased after forming self-assembled mono-layers (SAMs) used to capture the protein, which resulted from the negative charges of SAMs, and increased after forming protein by 11.5% at $V_{G}$ = 0 V due to the positive charges of protein.

Keywords

References

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