The Clinical and Cost Effectiveness of Medical Nutrition Therapy in Persons with Hypercholesterolemia

고콜레스테롤혈증 환자에 대한 영양치료요법의 임상 및 비용효과 분석

  • Son, Jeong-Min (Dept. of Food Service and Clinical Nutrition, Seoul National University Hospital) ;
  • No, Mi-Ra (Dept. of Food Service and Clinical Nutrition, Seoul National University Hospital) ;
  • Lee, Yeong-Hui (Dept. of Food Service and Clinical Nutrition, Seoul National University Hospital) ;
  • Im, Jeong-Hyeon (Dept. of Nutrition, Boramae Hospital)
  • 손정민 (서울대학교병원 급식영양과) ;
  • 노미라 (서울대학교병원 급식영양과) ;
  • 이영희 (서울대학교병원 급식영양과) ;
  • 임정현 (보라매병원 영안실)
  • Published : 2003.02.03

Abstract

Although medical nutrition therapy (MNT) is considered as a cornerstone of medical treatment for hypercholesterolemia, few studies have evaluated medical and economical outcome of MNT. This study was conducted to identify whether MNT administered by registered dieticians could lead to a beneficial clinical and cost outcome in persons with hypercholesterolemia. A prospective clinical trial was carried out at outpatient clinics, which involved an initial visit with a dietitian followed by another visit at first 4 weeks during the 6 weeks study periods. Thirty-nine subjects took part in a 6 weeks nutrition intervention program. Clinical and economical outcomes were compared before and after MNT. Medical nutrition therapy lowered total serum cholesterol level 6.1% (P<0.05), low-density lipoprotein cholesterol (LDL-C) 9.4% (P<0.05) and high-density lipoprotein cholesterol (HDL-C) 3.0% (P<0.05). The cost-effective ratio was ₩ 1,520/cholesterol mg/dl and ₩ 1,441/LDL-cholesterol mg/dl, respectively. After dietitian's intervention, lipid drug eligibility was obviated in 16 of 39(41%) subjects. The cost savings from the avoidance of lipid medications was ₩ 151,107 per patient annually. In conclusion, it is suggested that provision of systemic intensive nutritional care for persons with hypercholesterolemia has significant effects on serum cholesterol reduction and clinical cost savings.

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