Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
권호 표지

A Case of Osteosarcoma of the Mandible

좌측 하악골에 생긴 골육종(Osteosarcoma) 1예

  • Kim Chan-Jong (Department of Otolaryngology, University of Ulsan College of Medicine) ;
  • Lee Jae-Dong (Department of Otolaryngology, Masan Samsung Medical Cener) ;
  • Nam Soon-Yuhl (Department of Otolaryngology, University of Ulsan College of Medicine)
  • 김찬종 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 이재동 (마산삼성병원 이비인후과학교실) ;
  • 남순열 (울산대학교 의과대학 서울아산병원 이비인후과학교실)
  • Published : 2003.11.01
Download PDF
⟨ Previous Next ⟩

Abstract

Osteosarcoma is one of the most frequently occurring malignant bone tumor except for multiple myeloma. However, osteosarcoma of the mandible is rare and aggressive malignancy constituting about 5% to 13% of all cases of skeletal osteosarcoma. The authors experienced a case of osteosarcoma of the mandible in a 31-years old male patient. He visited our outpatient clinic with painless mass of the cheek. On the basis of the clinical and imaging findings, the differential diagnosis included giant cell tumor, histiocytosis and malignant bone tumor. In the first operation, the mass of the mandible was excised. Intraoperative microscopic examination of a frozen section did not yield a diagnosis: however, the final definitive histologic examination revealed osteoblastic osteosarcoma. After 15days, wide excision with hemimandibulectomy was completed followed by postoperative radiotherapy and chemotherapy. With our experience, we report the progression of diagnosis and management for mandibular osteosrcoma.

Keywords

References

  1. Abubaker AO, Braun TW, Sotereanos GC, Erickson ER : Osteosarcoma of the mandibular condyle. J Oral Maxillofacial Surg. 1986 ; 44 : 126-131 https://doi.org/10.1016/0278-2391(86)90195-3
  2. Zorzan G, Tullio A, Bertolini F, Sesenna E : Osteosarcoma of the mandibular condyle : case report. J Oral Maxillofacial Surg. 2001 ; 59 : 574-577 https://doi.org/10.1053/joms.2001.22694
  3. Garrington GE, Scofield HH, Cornyn J, Hooker SP : Osteosarcoma of the jaws : analysis of56 cases. Cancer. 1967 ; 20 : 77-91 https://doi.org/10.1002/1097-0142(1967)20:1<77::AID-CNCR2820200112>3.0.CO;2-A
  4. Caron AS, Hajdu SI, Strong EW : Osteogenic sarcoma of the facial and cranial bones: a review of forty-three cases. Am J Surg. 1971 ; 122 : 719-725 https://doi.org/10.1016/0002-9610(71)90434-X
  5. Clark L, Unni KK, Dahlin DC : Osteosarcoma of the jaw. Cancer. 1983 ; 51 : 2311-2316 https://doi.org/10.1002/1097-0142(19830615)51:12<2311::AID-CNCR2820511224>3.0.CO;2-Z
  6. Koh YC, Choi HC : A case of osteosarcoma arising from left maxilla. Korean J Otolaryngol. 1967 ; 10 : 103-105
  7. Lee SD, Hong RB : Osteogenic sarcoma of the maxilla. Korean J Otolaryngol. 1975 ; 20 : 33-36
  8. Mardinger O, Givol N, Tahni YP, Taicher S : Osteosarcoma of the jaw : The Chaim Sheba medical center experience. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 ; 91 : 445-451 https://doi.org/10.1067/moe.2001.112330
  9. Slow IN, Stern D, Friedman EW : Osteogenic sarcoma arising in preexisting fibrous dysplasia: Report of case. J Oral Surg. 1971 ; 29 : 126-129
  10. Arlen M : Radiation induced sarcoma of bone. Cancer. 1971 ; 28 : 1087-1090 https://doi.org/10.1002/1097-0142(1971)28:5<1087::AID-CNCR2820280502>3.0.CO;2-F
  11. Delgado R, Maafs E, Alfeiran A, et al : Osteosarcoma of the jaw. Head Neck. 1994; 16 : 246-252 https://doi.org/10.1002/hed.2880160307
  12. Undqvist C, Teppo L, Sane J, Holmstrom T, Wolf J : Osteosarcoma of the mandible. J Oral Maxillofacial Surg. 1986 ; 44 : 759-764 https://doi.org/10.1016/0278-2391(86)90149-7
  13. Dahlin DC : Bone tumors. 3rd ed. Springfield: Charles E. Thomas. 1978 : 226-273
  14. Bertoni F, Dallera P, Bacchini P, Marchetti C, Campobassi A : The Instituto Rizzoli-Beretta experience with osteosarcoma the jaw. Cancer. 1991 ; 68 : 1555-1563 https://doi.org/10.1002/1097-0142(19911001)68:7<1555::AID-CNCR2820680717>3.0.CO;2-0
  15. Rosen G, Marcove RC, Capparros B : Primary osteogenic sarcoma : the rationalefor preoperative chemotherapy and delayed surgery. Cancer. 1979 ; 43 : 2163-2177 https://doi.org/10.1002/1097-0142(197906)43:6<2163::AID-CNCR2820430602>3.0.CO;2-S
  16. Eliber FR, Rosen G : Adjuvant chemotherapy of osteosarcoma. Semin Oncol. 1989 ; 16 : 312-323
  17. Mark KG, Sercarz JA, Tran L, Dodd LG, Selch M, Calcaterr TC : Osteogenic sarcoma of the head and neck : the UCLA experience. Arch Otolaryngol Head Neck Surg. 1991 ; 117 : 761-766 https://doi.org/10.1001/archotol.1991.01870190073015
  18. Chambers RG, Mahoney WD : Osteogenic sarcoma of the mandibke : current management. Am J Clic Pathol. 1970 ; 54 : 625-636 https://doi.org/10.1093/ajcp/54.4.625
  19. Aymond AK, Ayala A, Spires J, et al : Osteosarcoma of head and neck. LAB Invest. 1989 ; 60 : 76A