Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
권호 표지

The effect of Phyllostachys nigra var. henenis Strapf leaf extract in the gamma-irradiated mice

방사선 조사 마우스에서 분죽(Phyllostachys nigra var. henenis Strapf)잎 추출물의 효과

  • Shin, Dong-Ho (College of Veterinary Medicine, Chonnam National University) ;
  • Kim, Jong-Choon (College of Veterinary Medicine, Chonnam National University) ;
  • Kim, Se-Ra (College of Veterinary Medicine, Chonnam National University) ;
  • Oh, Heon (College of Veterinary Medicine, Chonnam National University) ;
  • Park, In-Chul (College of Veterinary Medicine, Chonnam National University) ;
  • Oh, Ki-Seok (College of Veterinary Medicine, Chonnam National University) ;
  • Chung, Hee-Jong (College of Agriculture and Life Science, Chonnam National University) ;
  • Jang, Jong-Sik (Department of Animal Science, Sangju National University) ;
  • Kim, Sung-Ho (College of Veterinary Medicine, Chonnam National University)
  • 신동호 (전남대학교 수의과대학 수의학과) ;
  • 김종춘 (전남대학교 수의과대학 수의학과) ;
  • 김세라 (전남대학교 수의과대학 수의학과) ;
  • 오헌 (전남대학교 수의과대학 수의학과) ;
  • 박인철 (전남대학교 수의과대학 수의학과) ;
  • 오기석 (전남대학교 수의과대학 수의학과) ;
  • 정희종 (전남대학교 농업생명과학대학 응용생물공학부) ;
  • 장종식 (상주대학교 축산학과) ;
  • 김성호 (전남대학교 수의과대학 수의학과)
  • Accepted : 2003.02.20
  • Published : 2003.03.31
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Abstract

This study was performed to determine the effect of Phyllostachys nigra var. henenis Strapf leaf extract on jejunal crypt survival, endogenous spleen colony formation and apoptosis in jejunal crypt cells of mice irradiated with high and low dose of gamma-radiation. Phyllostachys nigra var. henenis Strapf administration before irradiation (I.P.: 125 mg/kg of body weight, at 24 hours before irradiation) resulted in an increase of the formation of endogenous spleen colony (p<0.01). The frequency of radiation-induced apoptosis was also reduced by pretreatment of Phyllostachys nigra var. henenis Strapf (I.P.: 280 mg/kg or 28 mg/kg of body weight, at 24 hours before irradiation, p<0.01). These results indicated that Phyllostachys nigra var. henenis Strapf might be a useful radioprotector, especially since it is a relatively nontoxic natural product. Further studies are needed to characterize better the promotion nature of Phyllostachys nigra var. henenis Strapf and its components.

Keywords

References

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