IMMUNE NETWORK
- Volume 3 Issue 3
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- Pages.242-247
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- 2003
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- 1598-2629(pISSN)
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- 2092-6685(eISSN)
Investigation of IL-1B (-511, +3954) and IL-1RN Gene Polymorphisms in Korean Psoriasis Patients
한국인 건선 환자에서의 IL-1B (-511, +3954)와 IL-1RN 유전자의 다양성 조사
- Kim, Yang-Kyum (Department of Microbiology, College of Medicine, The Catholic University of Korea) ;
- Pyo, Chul-Woo (Department of Microbiology, College of Medicine, The Catholic University of Korea) ;
- Kim, Tae-Yoon (Department of Dermatology, College of Medicine, The Catholic University of Korea) ;
- Kim, Tai-Gyu (Department of Microbiology, College of Medicine, The Catholic University of Korea)
- 김양겸 (가톨릭대학교 의과대학 미생물학교실) ;
- 표철우 (가톨릭대학교 의과대학 미생물학교실) ;
- 김태윤 (가톨릭대학교 의과대학 피부과교실) ;
- 김태규 (가톨릭대학교 의과대학 미생물학교실)
- Published : 2003.09.30
Abstract
Background: Psoriasis is an inflammatory skin disorder that is characterized by a marked proliferation of keratinocytes, vascular dilation and leukocyte infiltration. Cytokines play important roles in the pathogenesis of inflammatory disorders. An overexpression of proinflammatory cytokines was characterized in psoriasis plaque. Among these cytokines, IL-