Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Effects of Kamiguibi-tang on Learning Ability of Ehtanol-induced Rats

가미귀비탕이 알콜 중독된 흰쥐의 학습능력에 미치는 영향

  • Lee Sang Ryong (College of Oriental Medicine, Woosuk University) ;
  • Cui Xun (Department of Oriental Pharmacy, Woosuk University) ;
  • Lim Jong Pil (Department of Oriental Pharmacy, Woosuk University)
  • Published : 2003.08.01
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Abstract

This study was carried out to investigate effects of Kamiguibi-tang extract on learning ability of ethanol-treated rats. The rats were divided into 3 groups; normal, control and sample group. Control group administered ethanol at a dose of 3g/kg bw.(25 v/v %), while sample group administered the Kamiguibi-tang extract(200mg/kg) 30 min. before treating same dose of ethanol as control group orally. All groups were subjected to trials of straight channel on the 1 st day and to those of multiple T-maze during the following 3 days. The time required in normal group for the straight or T-maze of the 2nd and 3rd trials was significantly shorter than that of the 1 st, while the control group showed no significance. But in the straight channel or multiple T-maze trials, the sample group showed significant decrease in the time required against the control group and also showed significant decrease in the number of selecting errors.

Keywords

References

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