동의생리병리학회지 (Journal of Physiology & Pathology in Korean Medicine)

  • 제17권6호
  • /
  • Pages.1487-1492
  • /
  • 2003
  • /
  • 1738-7698(pISSN)
  • /
  • 2288-2529(eISSN)
대한동의생리학회·한의병리학회 ( The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine)
권호 표지

알레르기 반응에 미치는 건중탕의 효과

Effects of Gunjung-tang on Allergic Reaction

  • 강경화 (동의대학교 한의과대학 생리학교실ㆍ동의대학교 한의과대학 한의학연구소) ;
  • 최영현 (동의대학교 한의과대학 해부학교실ㆍ동의대학교 한의과대학 한의학연구소) ;
  • 최병태 (동의대학교 한의과대학 생화학교실ㆍ동의대학교 한의과대학 한의학연구소) ;
  • 이용태 (동의대학교 한의과대학 생리학교실ㆍ동의대학교 한의과대학 한의학연구소)
  • Kang Kyung Hwa (Department of Physiology, College of Oriental medicine, Research Institute of Oriental medicine, Dongeui University) ;
  • Choi Yung Hyun (Department of Anatomy, College of Oriental medicine, Research Institute of Oriental medicine, Dongeui University) ;
  • Choi Byung Tae (Department of Biochemistry, College of Oriental medicine, Research Institute of Oriental medicine, Dongeui University) ;
  • Lee Yong Tae (Department of Physiology, College of Oriental medicine, Research Institute of Oriental medicine, Dongeui University)
  • 발행 : 2003.12.01
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초록

Gunjung-tang(GJT) has been reported at Shanghanlun(傷寒論), which has been used for the treatment of general weakness, digestive organ disease and the treatment of allergic disorders in clinical medicine. However, its effect in experimental models remains unknown. In a rat and mouse model, the role of GJT was examined in mast cell-dependent allergic reactions and secretion of inflammatory cytokines. GJT inhibited anti-dinitrophenyl IgE antibody-induced passive cutaneous anaphylaxis reaction by Intraperitoneal pretreatment. GJT inhibited both IL-1β and TNF-α secretion on egg albumin induced allergic tissues and compound 48/80 induced thymus. Furthermore, GJT enhanced Band T lymphocytes proliferation. Our findings provide evidence that GJT inhibits the IgE-dependent allergic reactions and inflammatory cytokines secretion, and enhanced immune response.

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참고문헌

  1. 最新免疫學 李淵台
  2. 韓方醫藥學 金一赫;趙弼衡(譯)
  3. 免疫學 서울대학교醫科大學(編)
  4. 免疫生物學 김태규(외)
  5. 耳鼻咽喉科學 盧寬澤
  6. 最新耳鼻咽喉科學 白萬基
  7. 景岳全書 張介賓
  8. 傷寒論譯詮 蔡仁植
  9. 原色臨床本草學 辛民敎
  10. 석사학위논문 小建中湯加 龍骨.牡蠣가 흰쥐의 實驗的 胃潰瘍에 미치는 影響 金兌仲
  11. 박사학위논문 The antioxidant effect, cell viability and the effect to the gene expression using cDNA microarray assay of Shogunjung-tang ga yongglo.morea 金兌仲
  12. 석사학위논문 小建中湯과 六辰丹이 白鼠의 成長發育에 미치는 影響 尹漢龍
  13. 석사학위논문 黃耆建中湯合理中湯이 抗遺瘍 및 胃腸管 機能에 미치는 效果에 對한 實驗的 硏究 成銀美
  14. 석사학위논문 黃　建中湯 및 加味黃　建中湯이 흰쥐의 運動 疲勞恢復에 미치는 影響 趙仁珠
  15. Microbiol. Immunol. v.22 A new method for extraction of extravasated dye in the skin and the influence of fasting stress on passive cutaneous allergy in guinea pigs and rats Katayama, S.;Shionoya, H.;Ohtake, S.
  16. J. Immunol. v.162 Role of TGF-beta1 on the IgE-dependent anaphylaxis reaction Kim, H.M.;Lee, Y.M.
  17. J. Biol. Chem. v.252 Native heparin from rat peritoneal mast cells Yurt, R.W.;Leid, R.W.;Austen, K.F.
  18. J. Pharmacol. Exp. Ther. v.127 A method for fluorometric assay of histamine in tissues Shore, P.A.;Burkhalter. A.;Cohn, V.H.
  19. Cellular, Molecular, and Clinical Aspects of Allergic Disorders Mediators of immediate hypersensitivity Ho, P.C.;Lewis, R.A.;Austen, K.F.;Orange, R.P.;Gupta, S.;Good, R.A.(Eds.)
  20. Int. J. Orient. Med. v.1 Antiallergy drugs from Oriental medicines Kim, H.M.
  21. Acta Ophthalmol. v.192 Ocular anaphylaxis induced in the rat by topical application of compound 48/80. Dose response and time course study Allansmith, M.R.;Baird, R.S.;Ross, R.N.;Barney, N.P.;Bloch, K.J.