Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effects of Ginseng Radix and Ophiopogonis Tuber on Field Potentials in Rat Hippocampal and Cardiac Muscle Slices

인삼과 맥문동이 흰쥐 뇌와 심장의 field potential에 미치는 영향

  • Lee Choong Yeol (Department of Physiology, College of Oriental Medicine, Kyungwon University)
  • 이충열 (경원대학교 한의과대학 생리학교실)
  • Published : 2003.12.01
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Abstract

In the present study, the effects of Ginseng radix and Ophiopogonis tuber on field potentials in rat hippocampal slices and cardiac muscle slices were investigated by multi-channel extracellular recording using MED64 system. The field potentials in the brain slices represent synaptic transmission and nerve excitability, and the field potentials in heart muscles represent muscle contractility. The present results show that the aqueous extract of Ginseng radix enhanced field potentials in the both hippocampal slices and cardiac muscle slices. In contrast, the aqueous extract Ophiopogonis tuber exerted no significant effect on the field potentials in the hippocampal slices and cardiac muscle slices. These results suggest the possibility that Yin-Yang theory could be studied in relation with excitability in neurons and muscles.

Keywords

References

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