Clinical and Experimental Reproductive Medicine

The Korean Society for Reproductive Medicine (대한생식의학회)
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Successful Pregnancy by ICSI using Spermatozoa Banked Prior to Bone Marrow Transplantation for Severe Apalstic Anemia and Chronic Myelogenous Leukemia

만성 골수성 백혈병과 재생 불량성 빈혈로 진단받은 환자의 치료 전 동결보존된 정자를 이용한 세포질내 정자주입술로 임신에 성공한 2례

  • Han, Jee-Eun (Department of Obstetrics and Gynecology, CHA General Hospital, College of Medicine, Pochon CHA University) ;
  • Chung, Tae-Gyu (Department of Urology, CHA General Hospital, College of Medicine, Pochon CHA University) ;
  • Chung, Mi-Kyung (Infertility Medical Center, CHA General Hospital, College of Medicine, Pochon CHA University) ;
  • Min, Woo-Sung (Department of Internal Medicine, College of Medicine, Catholic University) ;
  • Lee, Sook-Hwan (Department of Obstetrics and Gynecology, CHA General Hospital, College of Medicine, Pochon CHA University) ;
  • Yoon, Tae-Ki (Department of Obstetrics and Gynecology, CHA General Hospital, College of Medicine, Pochon CHA University)
  • 한지은 (포천중문 의과대학 산부인과학교실) ;
  • 정태규 (포천중문 의과대학 비뇨기과학교실) ;
  • 정미경 (포천중문 의과대학 불임의학연구실) ;
  • 민우성 (가톨릭대학교 의과대학 내과학교실) ;
  • 이숙환 (포천중문 의과대학 산부인과학교실) ;
  • 윤태기 (포천중문 의과대학 산부인과학교실)
  • Published : 2003.06.30
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Abstract

Objective: To report tow cases of successful pregnancies following long term cryopreserved spermatozoa prior to bone marrow transplantation (BMT) for chronic myelogenous leukemia (CML) and severe aplastic anemia (SAA). Materials and Methods: Case report. Results: With the first case, after cryopreservation of semen from 25 year-old man with CML prior to BMT, his wife is being pregnant by intracytoplasmic sperm injection (ICSI) using thawed spermatozoa. With the second case, 28 year-old man with SAA became father by ICSI using banked spermatozoa before BMT. Conclusion: These cases support that men with malignancy have the chance of fathering their own genetic children. It is important therefore, to increase the awareness of clinicians especially oncologists and patients themselves to the new developments in preserving fertility for cancer patients.

Keywords

References

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