Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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Effect of (-)-epigallocatechin-3-gallate on lipogenesis in 3T3-L1 Cell

  • Kang, Shin-Seok (Northern Branch, Chungbuk Livestock and Veterinary Research Institute) ;
  • Park, Jae-Myung (Northern Branch, Chungbuk Livestock and Veterinary Research Institute) ;
  • Choi, Hae-Yeon (Northern Branch, Chungbuk Livestock and Veterinary Research Institute) ;
  • Cho, Woo-Young (Northern Branch, Chungbuk Livestock and Veterinary Research Institute) ;
  • Lee, Jong-In (Northern Branch, Chungbuk Livestock and Veterinary Research Institute)
  • Published : 2003.12.01
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Abstract

We studied the effect of epigallocatechin-3-gallate(EGCG) on the adipose conversion of 3T3-L1 cells by insulin. In the 10 days of culture with insulin, the fat cells exhibited the increased and larger intracytoplasmic lipid droplets. In contrast, the levels of triglyceride(TG), a marker of adipose conversion, were decreased. However, the levels of glucose were decreased in the adipose conversion. In addition, levels of cholesterol were decreased in the differentiated 3T3-L1 cells.

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References

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