Study of Substance Changes in Flowers of Pueraria $thunbergiana_{Benth.}$ During Storage

  • Kim, Chung-Sook (Drug Research and Development Team, Korea Institute of Oriental Medicine) ;
  • Shin, Sun-Mi (Drug Research and Development Team, Korea Institute of Oriental Medicine) ;
  • Ha, Hyek-Yung (Drug Research and Development Team, Korea Institute of Oriental Medicine) ;
  • Kim, Jong-Moon (Drug Research and Development Team, Korea Institute of Oriental Medicine)
  • Published : 2003.03.01

Abstract

Puerariae Flos is a traditional herbal medicine that has long been used as a treatment for colds, diabetes, and hangovers. The herbal medicine contains a wide variety of isoflavones such as kakkalide, tectoridin, and tectorigenin. This study demonstrates that the substances undergo a certain degree of change depending on the storage period by the method of HPLC and $^{13}C-NMR$, and that the HPLC analysis can be used to determine the freshness of Puerariae Flos.

Keywords

References

  1. Arao, T., Udayama, M., Kinjo, J., Nohara, Y., Funakoshi, T., and Kojima, S., Preventive effects of saponins from Puerariae radix (the root of Pueraria lobata Ohwi) on in vitro immunological injury of rat primary hepatocyte cultures. Biological & Pharmaceutical Bulletin, 20, 988 (1997) https://doi.org/10.1248/bpb.20.988
  2. Hwang, B. Y., Gu, T. H., Lee, J. H., Roh, J. S., Lee, K. S., and Lee, J. J., Inhibition of inflammatory mediators by sesquiter-penes from Ligularia fischerii. The 29th annual meeting of the Korean Society of Pharmacognosy, 72 (1998)
  3. Kim, C. M., Shin, M. K., Ahn, D. K., and Lee, K. S., Encyclopaedia of Chinese Medicine. Jungdam Publishers, Seoul, Vol. 1, pp. 62-63 (1998)
  4. Kinjo, J. E., Takeshita, T., Abe, Y., Terada, N., Yamashita, H., Yamasaki, M., Takeuchi, K., Murakami, K., Tomimatsu, T., and Nohara, T., Studies on the constituents of Pueraria lobata. Chemical constituents in the flowers and the leaves. Chemical & Pharmaceutical Bulletin, 36(3), 1174-1179 (1987) https://doi.org/10.1016/0006-2952(87)90431-X
  5. Kinjo, J. E., Takeshita, T., and Nohara, T., Studies on the constituents of Pueraria lobata V. A tryptophan derivative from Puerariae Flos. Chemical & Pharmaceutical Bulletin, 36(10), 4171-4173 (1988) https://doi.org/10.1248/cpb.36.4171
  6. Kubo, M., Sasaki, M., Namba, K., Naruto, S., and Nishimura H., Isolation of a new isoflavone from Chinese Pueraria flowers. Chemical & Pharmaceutical Bulletin, 23(10), 2449-2451 (1975) https://doi.org/10.1248/cpb.23.2449
  7. Kurihara, T. and Kikuchi, M., Studies on the constituents of flowers. On the components of flowers of Pueraria thunbergiana Benth. Yakugaku Zasshi, 93, 1201 (1973) https://doi.org/10.1248/yakushi1947.93.9_1201
  8. Kurihara, T., and Kikuchi, M., Studies on the constituents of flowers V. On the components of flowers of Pueraria thunbergiana Benth. (2). Isolation of a new isoflavone glycoside. Yakugaku Zasshi, 95(11), 1283-1285 (1975) https://doi.org/10.1248/yakushi1947.95.11_1283
  9. Kurihara, T., and Kikuchi, M., Studies on the constituents of flowers IV. On the components of flowers of Pueraria thunbergiana Benth. (3). Yakugaku Zasshi, 96, 1486 (1976) https://doi.org/10.1248/yakushi1947.96.12_1486
  10. Lee, K. T., Sohn, I. C., Kong, E. A., Kim, D. H., Choi, S. K., Choi, J. W., and Park, H. J., Antioxidative and cytoprotective effects of isoflavones isolated from Pueraria thunbergiana flowers. Yakhak Hoeji, 43(6), 736-742 (1999)
  11. Li, Y. Q., Lu, R. R., and Wei, L. X., Study on flavonoides of Iris dichotoma pall. Acta Pharmaceutica Sinica, 21(11), 836-841 (1986)
  12. Park, H. J., Park, J. H., Moon, J. O., Lee, K. T., Jung, W. T., OH, S. R., and Lee, H. K., Isoflavone glycosides from the flowers of Pueraria thunbergiana Phytochemistry, 51, 47 (1999)
  13. Yoshikoshi, M., Yoshiki, Y., Okubo, Y., Seto, K., and Sasaki Y., Prevention of hydrogen peroxide damage by soybean saponins to mouse fibroblasts. Planta Medica, 62, 252 (1996) https://doi.org/10.1055/s-2006-957871