The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
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Effects of Low Power Laser for the Expression of Substance P in the Burned Skin of the Rats

흰쥐의 피부화상 후 저강도 레이저 조사가 Substance P의 발현에 미치는 영향

  • Koo Hyun-Mo (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Daegu University) ;
  • Lee Sun-Min (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Daegu University) ;
  • Nam Ki-Won (Lab. of Nerve regeneration, Dept. of Rehabilitation Science, Daegu University) ;
  • Kim Souk-Boum (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Daegu University) ;
  • Cheon Song-Hee (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Daegu University) ;
  • Kang Jong-Ho (Major in Physical Therapy, Graduate School of Rehabilitation Science, Daegu University) ;
  • Kim Jin-Sang (Department of Physical Therapy, College of Rehabilitation Science, Daegu University)
  • 구현모 (대구대학교 대학원 재활과학과 물리치료) ;
  • 이선민 (대구대학교 대학원 재활과학과 물리치료) ;
  • 남기원 (대구대학교 재활과학대학 물리치료학과 신경재생실) ;
  • 김석범 (대구대학교 대학원 재활과학과 물리치료) ;
  • 천송희 (대구대학교 대학원 재활과학과 물리치료) ;
  • 강종호 (대구대학교 재활과학대학원 물리치료) ;
  • 김진상 (대구대학교 물리치료학과)
  • Published : 2003.09.01
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Abstract

This study was performed to investigate the effect of low power laser irradiation on Substance P(SP) expression in the burned skin of the rats. Burns of about 3cm in diameter were created with $75^{\cric}C$ water on the back of the rats, and the lesion of experimental group were irradiated on days 1, 2, 3 and 4 postwounding. Control leasions were not irradiated. After burns, low power laser irradiation was applied by using 1000Hz, 830nm GaAlAs(Gallium-aluminum-arsenide) semiconductor diode laser. The expression of evaluated Substance P(SP) immunohistochemistry on rabbit anti-SP The results of this study wereas follows 1. The Substance P was expressed in the lamina I and II of dorsal horn of spinal cord. In expression of SP, the lesion of control group made SP to more induce significantly than experimental leasions. 2. SP immunoreactivity in burned leasion of spinal cord were decreased markedly 4 days after burns, and decreased gradually from 1 day to 2 days in burns which is laser irradiation These data suggest that low power laser have a pain release effect in the burned skin of the rats.

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