Effects of chewable tablet containing sodium fluoride and xylitol on the oral hygiene state in the orthodontic patients

자일리톨과 불화나트륨을 함유한 저작성 정제가 교정환자의 구강위생에 미치는 영향에 관한 임상시험

  • Yu, Sang-Hoon (Department of Orthodontics, College of Dentistry, Seoul National University) ;
  • Ahn, Sug-Joon (Department of Orthodontics, College of Dentistry, Seoul National University) ;
  • Lee, Shin-Jae (Department of Orthodontics, College of Dentistry, Seoul National University) ;
  • Baek, Seung-Hak (Department of Orthodontics, College of Dentistry, Seoul National University) ;
  • Kim, Tae-Woo (Department of Orthodontics, College of Dentistry, Seoul National University) ;
  • Chang, Young-Il (Department of Orthodontics, College of Dentistry, Seoul National University) ;
  • Nahm, Dong-Seok (Department of Orthodontics, College of Dentistry, Seoul National University)
  • 유상훈 (서울대학교 치과대학 교정학교실) ;
  • 안석준 (서울대학교 치과대학 교정학교실) ;
  • 이신재 (서울대학교 치과대학 교정학교실) ;
  • 백승학 (서울대학교 치과대학 교정학교실) ;
  • 김태우 (서울대학교 치과대학 교정학교실) ;
  • 장영일 (서울대학교 치과대학 교정학교실) ;
  • 남동석 (서울대학교 치과대학 교정학교실)
  • Published : 2003.04.01

Abstract

The aim of this study was to evaluate the effect a chewable tablet containing sodium fluoride and xylitol (DenPo, Hamizzle, Bucheon, Kyungki) on the oral hygiene state in the orthodontic patients.'rho subjects consisted of 30 adult orthodontic patients, who have worn the fixed orthodontic appliance at least 6 months. They were instructed to use the tablet forth a day, Gingival index (GI), plaque index (PI), and sulcus bleeding index (SBI) of upper and lower anterior and posterior regions were measured before using the tablet (T0), 2 weeks after using the tablet (T1), and 4 weeks after using the tablet (T2). The data were analyzed with Wilcoxon signed ranks tests. The results were as follows ; 1 PI was decreased significantly in the T1 and T2 stage compared with T0 stage in the both anterior and posterior regions (p<0.05). Although PI was decreased in the T2 stare compared with T1, there was not statistical significance (p>0.05). 2. GI and SBI showed similar results compared with PI. In the T1 and T2 stage, there was statistically significant decrease in the GI and SBI (p<0.05), This study showed that the DenPo tablet could be used as an adjunct to improve oral hygiene in the orthodontic patients. The decrease of the indices nay suggest that DenPo tablet could be effective in the plaque removal and prevention of gngival inflammation in the orthodontic patients.

본 연구는 불화나트륨과 자일리톨 성분으로 구성된 구강 청정용 저작성 정제 (덴포정, 하미 즐, 부천, 경기 )가 교정치료 중인 환자의 구강위생 상태에 미치는 영향을 알아보기 위해 시행되었다. 교정치료 중인 18세 이상의 성인 환자 30명을 대상으로 약제사용 전, 2주 후, 4주 후에 피험자의 상악과 하악 전치 부위 및 구치 부위에서 각각 치은 지수, 치은 출혈 지수, 치태 지수를 측정하여 다음과 같은 결과를 얻었다. 1. 상하악 전치부와 구치부 모두에서 치태 지수가 약제사용 전에 비해 사용 2주 후와 4주 후 유의성 있게 감소하였다. (p<0.05).또한, 적용 2주 후와 4주 후의 지수를 비교하였을 때 4주 후에 좀 더 개선된 경향을 보였으나, 통계적 유의성은 나타나지 않았다(p>0.05). 2. 치은 지수, 치은 출혈 지수도 상하악 전치부와 구치부 모두에서 적용 전에 비하여 2주 후와 4주 후 유의성 있게 감소하였다(p<0.05).적용 2주 후와 4주 후의 지수의 비교 검증에서 통계학적으로 유의할 만한 차이는 보이지 않아 구강위생 상태의 개선이 계속 유지됨을 보였다. 본 연구의 결과는 치태 지수, 치은 지수, 치은 출혈 지수가 실험 정제 적용 후에 감소하여 구강위생 상태가 개선되었음을 보였다. 이러한 결과를 통해 덴포정을 교정치료 중인 한자에서 부가적으로 사용하였을 경우 치주조직의 건강을 증진시키는데 도움을 줄 수 있으리라고 생각된다.

Keywords

References

  1. Basdra EK, Huber H, Komposch G. Fluoride release from orthodontic bonding agents alters the enamel surface and inhibitsenameldemineralization in vitro. Am J Orthod Dentofac Orthop 1996 : 109: 466-72
  2. Ogaard B, Rolla G, Arends J, ten Cate JM. Orthodontic appliances and enamel demineralization, part 1 : lesion development. Am J Orthod Dentofac Orthop 1988 : 94 : 68-73 https://doi.org/10.1016/0889-5406(88)90453-2
  3. Ogaard B, Larsson E, Henriksson T, Birkhed D, Bishara SE. Effects of combined application of antimicrobial and fluoride varnish in orthodontic patients. Am J Orthod Dentofac Orthop 2001 : 120: 28-35
  4. Gwinnett AJ, Ceen RF. Plaque distribution on bonded brackets : a scanning microscope study. Am J Orthod Dentofac Orthop 1979 : 75 : 667-77 https://doi.org/10.1016/0002-9416(79)90098-8
  5. Sakamaki ST, Bahn AN. Effect of orthodontic banding on localized oral lactobacilli. J Dent Res 1968 : 47 : 275-79
  6. Ogaard B. Prevalence of white spot lesions in 19-year-olds : a study on untreated and orthodontically treated persons 5 years after treatment. Am J Orthod Dentofac Orthop 1989 : 96 : 423-7 https://doi.org/10.1016/0889-5406(89)90327-2
  7. Batoni G, Pardini M, Giannotti A, Ota F, Giuca MR, Gabriele M, Campa M, Senesi S. Effect of removable orthodontic appliances on oral colonisation by mutans streptococci in children. Eur J Oral Sci 2001 : 109: 388-92
  8. Lundstrom F, Krasse B. Streptococcus mutans and lactobacilli frequency in orthodontic patients; the effect of chlorhexidine treatments. Europ J Orthod 1987 : 9 : 109-16
  9. 이하진, 장영일. 교정환자에 있어 chlorhexidine varnish 처치 전후의 치태내 균주변화에 관한 연구. 대치교정지 1997 : 27 : 173? 80
  10. Ortendahl T, Thilander B, Svanberg M. Mutans streptococci and incipient caries adjacnet to glass ionomer cement or resin-based composite in orthodontics. Am J Orthod Dentofac Orthop 1997 : 112 : 271-4
  11. Loesche WJ, Grossman NS, Earnest R, Corpron R. The effect of chewing xylitol gum on the plaque and saliva levels of Strepto coccus mutans. JADA 1984 : 108 : 587-592
  12. Harjola D, Liesmaa H. Effect of polyol and sucrose candies on plaque, gingivitis and lactobacillus index scores : Observations on Helsinki school children. Acta Odontol Scand 1978 : 36 : 237-42 https://doi.org/10.3109/00016357809004674
  13. Silness J, Loe H. Periodontal disease in pregnancy. II Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964 : 22 : 121-29
  14. Loe H, Silness J Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963 : 21 : 533-41
  15. Muhlernann HR. Son S. Gingival sulcus bleeding a leading symptom in initial gingivitis. Helv Odontol Acta 1971 : 15 : 107-13
  16. Zachrisson BD. Cause and prevention of injuries to teeth and supporting structures during orthodontic treatment. Am J Orthod Dentofac Orthop 1976 : 69 : 285-300
  17. Boyd RL. Longitudinal evaluation of a system for self-monitoring plaque control effectiveness in orthodontic patients. J Clin Periodontol 1983 : 10 : 380-8
  18. Boyd RL, Leggott PJ, Quinn RS, Eakle WS, Chambers D. Periodontal implications of orthodontic treatment in adults with reduced or normal periodontal tissues versus those of adolescents. Am J Orthod Dentofac Orthop 1989 : 96 : 191-8 https://doi.org/10.1016/0889-5406(89)90455-1
  19. Slots J. Microflora in the healthy gingival sulcus in man. Scand J Dent Res 1977 : 85 : 247-54
  20. Page RC, Schroeder HE. Pathogenesis of inflammatory periodontal disease. Lab. Invest. 1976 : 34 : 235-49
  21. McGhee JR, Michalek SM, cassel GH. Dental microbiology. Harper & Row publishers. Philadelphia
  22. Loesche WJ : Chemotherapy of dental plaque infection, Oral Sci Rev 1976 : 9 : 63-107
  23. Lamont RJ, Gil S, Demuth DR, Malamud D, Rosan B, Molecules of Streptococcus gordonii that bind to Prophyromonas gingivalis, Microbiol 1994 : 140: 867-72
  24. Cook GS, Costerton JW, Lamont RJ. Biofilm formation by Porphyromonas gingivalis and Streptococcus gordonii. J Periodon Res 1998 : 33 : 323-27
  25. Silverstone LM. Laboratory studies on the demineralization and demineralization of human enamel in relation to caries mechanisms. Aust Dent J 1980 : 25 : 163-8
  26. MKinen KK. Sweeteners and prevention of dental careis (Special reference to xylotol). Oral Health 1988 : 78 : 57-66
  27. Bowden GHW. Hamilton IR : Environmental pH as a factor in the conpetition between strains of the oral streptococci S. mutans, S. sanguis and S. mitier growing in continuous culture. Can J Microbiol 1987 : 33 : 824-27 https://doi.org/10.1139/m87-143
  28. 신승철, 이건수, 김성영, 김종배. 아동을 대상으로 한 정제형 불소함유구강세정제의 치연세균막제거 및 치은염완화효과에 관한 임상적 실험 연구. 대구보건지 1999 : 23 : 151-62