성견골수줄기세포의 신경세포로의 분화

DIFFERENTIATION OF ADULT CANINE BONE MARROW STEM CELLS INTO NEURONS

  • 최병호 (연세대학교 치과대학 구강악안면외과학교실 (원주기독병원)) ;
  • 허진영 (울산대학교 강릉아산병원 치과) ;
  • 박동균 (연세대학교 원주의과대학 이비인후과학교실) ;
  • 김병용 (Me-Plus 치과) ;
  • 이승호 (카톨릭 치과병원) ;
  • 박선영 (연세대학교 치과대학 구강악안면외과학교실 (원주기독병원))
  • 발행 : 2003.02.28

초록

In this study, we showed that neurons could be generated from adult canine bone marrow stem cells by culturing with $DMSO/BHA/FeCl_2$. These neurons differentiated from the bone marrow stem cells formed neurites, expressed neuron-specific markers. This differentiation was enhanced by $FeCl_2$. These results suggest that iron can effectively initiate differentiation of adult bone marrow stem cells into neurons.

키워드

참고문헌

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