Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
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Highly purified chitosan reduce blood alcohol concentration, aspartate aminotransferase, and alanine aminotransferase levels in human

  • Chung, Hwan-Suck (College of Pharmacy, Wonkwang University, and KI Co., Ltd.) ;
  • Koo, Hyun-Na (College of Pharmacy, Wonkwang University, and KI Co., Ltd.) ;
  • Moon, Young-Hoe (Department of Clinical Pathology, Wonkwang University School of Medicine) ;
  • Kim, Hyung-Min (College of Pharmacy, Wonkwang University, and KI Co., Ltd.)
  • Published : 2003.02.28
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Abstract

The purpose of this study was to examine the effect of supplementary highly purified chitosan (HPC) on blood alcohol concentration in healthy human. The human study was performed with two sections. Each section of the study was conducted by two-phase cross-over design with a week wash-out period. All volunteers took HPC in one phase, and took a placebo in the next phase. Blood alcohol concentrations were different between in those taking HPC and in those taking the placebo in the human. And the concentration of serum aspartate aminotransferase (AST, GOT) and alanine aminotransferase (ALT, GPT), the indicator of liver cell damage, was lowered in those taking HPC, compared to those taking the placebo. In conclusion, taking HPC prior to drinking alcohol can somewhat reduce alcohol concentration in human blood and liver cell damage.

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References

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