Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

A Study on the Change of Blood Constituents During Growth Period of Velvet Antler in Korean Spotted Deer

꽃사슴의 녹용 성장기간 중 혈액성분의 변화에 관한 연구

  • Kim, M.H. (Korea Nokyong Research Center, College of Natural Sciences, Konkuk University) ;
  • Kim, Y.S. (Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
  • Jeon, B.T. (Korea Nokyong Research Center, College of Natural Sciences, Konkuk University) ;
  • Moon, S.H. (Korea Nokyong Research Center, College of Natural Sciences, Konkuk University)
  • 김명화 (건국대학교 한국녹용연구센터) ;
  • 김영식 (서울대학교 천연물과학연구소/약학대학) ;
  • 전병태 (건국대학교 한국녹용연구센터) ;
  • 문상호 (건국대학교 한국녹용연구센터)
  • Published : 2003.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

This study was carried out to evaluate the change of blood constituents during the growth of antlers in Korean spotted deer (Cervus nippon). Samples of blood, obtained from the jugular vein of twenty five deer (3 to 6 year-old males) were taken in 10 days interval from casting to cutting of antler and were analyzed the blood parameters. Total-protein concentration in blood serum showed significantly differences during growth period of velvet antler (p<0.01), and it had similar tendency for total protein and albumin concentration, but albumin concentration was about 40-45% of total protein concentration. Urea and creatinine concentration was tended to inverse proportion, and it was almost 30:1 for ratio of urea and creatinine concentration. The concentration of total protein, creatinine, and uric acid concentration in blood during growth period of velvet antler was similarly increased and decreased but urea concentration was opposed. The concentration of total-bilirubin and direct-bilirubin at casting was higher than those at other period(P<0.05).

Keywords

References

  1. Audige, L. (1992) Serum biochemical values of rusa deer (Cervus timorensis rusa) in new Caledonia. Australian Veterinary Journal 69: 268-271 https://doi.org/10.1111/j.1751-0813.1992.tb09887.x
  2. Axelrod, J. and Reisine, T. D. (1984) Stress hormones : Their interaction and regulation. Science 224: 452-459 https://doi.org/10.1126/science.6143403
  3. Blum J. W, Kunz, P., Bachmann, C., and Colombo, J. P. (1981) Metabolic effects offasting in steers. Res. Vet. Sci. 31: 127-129 https://doi.org/10.1126/science.31.787.127
  4. Brown, R. D., Chao, C. C., and Faulkner, L. W. (1983) Hormone levels and antler development in white-tailed and sika fawns. Comp. Biochem. Physiol. 75A(3): 385-390
  5. Chapple, R. S., English, A. W., Mulley, R. C., and Lepherd, E. E. (1991) Haematology and serum biochemistry of captive unsedated chital deer (Axis axis) in Australia. Journal of Wildlife Diseases. 27: 396-406
  6. Chatterton, R. T. (1990) The role of stress in female reproduction: animal and human consideration. Int. J. Fertil. 35: 8-13
  7. DelGiudice, G. D., Mech, L. D., Seal, U. S., and Kams, P.D. (1987) Effects of winter fasting and refeeding on white-tailed deer blood profiles. J. Wildl. Manage. 51(4): 865-873 https://doi.org/10.2307/3801753
  8. Garcia, R. L., Sadighi, M., Francis, S. M., Suttie, J. M., and Fleming, J. S. (1997) Expression of neurotrophin-3 in the growing velvet antler of the red deer Cervus elaphus. Journal of Molecular Endocrinology 19: 173-182 https://doi.org/10.1677/jme.0.0190173
  9. Hyvarinen, H., Helle, T., Nieminen, M., Vayrynen, P., and Vayrynen, R. (1976) Some effects of handling reindeer during gatherings on the composition of their blood. Anim. Prod. 22: 105-114 https://doi.org/10.1017/S0003356100035479
  10. Hyvarinen, H., Helle, T., Vayrynen, R., and Vayrynen, P. (1975) Seasonal and nutritional effects on serum proteins and urea concentration in the reindeer (Rangifer tarandus tarandus L.). Br. J. Nutr. 33: 63-72 https://doi.org/10.1079/BJN19750009
  11. Klinger, S. R., Robel, R. J., Brown, B. A., and Brent, B. E. (1986) Blood characteristics of white-tailed deer from northeastern Kansas. J. Wildl. Dis. 22: 385-388
  12. Larsen, T. S., Lgercrantz, H., Riemersma, R. A., and Blix, A. S. (1985) Seasonal changes in blood lipids, adrenaline, noradrenaline, glucose and insulin in Norwegian reindeer. Acta Physiol. Scand. 124: 53-59 https://doi.org/10.1111/j.1748-1716.1985.tb07631.x
  13. Nieminen, M. (1980) Nutritional and seasonal effects on the haemotology and blood chemistry in reindeer (Rangifer tarandus tarandus L.). Comp. Biochem. Physiol. 66A: 399-413
  14. Nieminen, M. and Heiskari, U. (1989) Diets of freely grazing and captive reindeer during summer and winter. Rangifer 9: 17-34
  15. Rehbinder, C. and Edqvist, L. E. (1981) Influence of stress on some blood constituents in reindeer (Rangifer tarandus L). Acta Vet. Scand. 22: 480-492
  16. Reid, T. C. and Towers, N. R. (1985) Blood parameters of normal farmed deer. In biology of deer production. The Royal Society of New Zealand Bulletin 22: 73-76
  17. Rick, W. (1992) Klinische Chemie und Mikroskopie. Sechste, uberarbeitete und erweitere Auflage. Springer hungarica Ltd., Debrecen
  18. SAS package. (1985) SAS Institute Inc
  19. Sempere, A. J., Bubenik, G. A., and Smith, J. H. (1986) Antler cycle and thermolabile and thermostable alkaline phosphatase in white-tailed deer; circannual and circadian rhythms and variation after thyroxine, dexamethasone and ACTH administration. Acta Endocrinologica 111: 133-139
  20. Sempere, A. J., Grimberg, R., Silve, C., Tau, C., and Garabedian, M. (1989) Evidence for extrarenal production of 1,25-dihydroxyvitamin during physiological bone growth: In Vivo and In VItro production by deer antler cells. Endo. Vol. 125, No.5
  21. Soveri, T., Sankari, S., and Nieminen, M. (1992) Blood chemistry of reindeer calves (Rangifer tarandus) during the winter season. Comp. Biochem. Physiol. l02A. 1: 191-196
  22. Valtonen, M. and Eriksson, L. (1977) Responses of reindeer to water loding, water restriction and ADH. Acta. Physiol. Scand. 100: 340-346 https://doi.org/10.1111/j.1748-1716.1977.tb05959.x
  23. Zomborszky, Z., Feher, T., Horn, Eva., Poteczin, Eva., Tubolt, S., and Zomborszky, M.K. (1996) Comparison of some blood parameters of captured and farmed red deer (Cervus elaphus) hinds. Acta Veterinaria Hungarica. 44(4): 433-441
  24. 신국현(1987) 호범생약 연구보고서
  25. 이귀녕, 이종순(1996) 임상병리파일