Antioxidative Constituents of Hedyotis diffusa Willd.

  • Permana, Dharma (Laboratory of Phytomedicines, Institute of Bioscience, Universiti Putra Malaysia) ;
  • Lajis, Nordin Hj. (Laboratory of Phytomedicines, Institute of Bioscience, Universiti Putra Malaysia) ;
  • Abas, Faridah (Laboratory of Phytomedicines, Institute of Bioscience, Universiti Putra Malaysia) ;
  • Othman, A. Ghafar (Laboratory of Phytomedicines, Institute of Bioscience, Universiti Putra Malaysia) ;
  • Ahmad, Rohaya (Laboratory of Phytomedicines, Institute of Bioscience, Universiti Putra Malaysia) ;
  • Kitajima, Mariko (Faculty of Pharmaceutical Sciences, Chiba University) ;
  • Takayama, Hiromitsu (Faculty of Pharmaceutical Sciences, Chiba University) ;
  • Aimi, Norio (Faculty of Pharmaceutical Sciences, Chiba University)
  • Published : 2003.03.01

Abstract

The antioxidative constituents isolated from Hedyotis diffusa were identified as quercetin 3-O-${\beta}$-rutinoside (1) and quercetin 3-O-${\beta}$-glucoside (2). We also isolated asperuloside (3) from this plant. Identification was done based on spectroscopic analysis. Quercetin 3-O-${\beta}$-rutinoside was the stronger antioxidant than quercetin 3-O-${\beta}$-glycoside while asperuloside was inactive.

Keywords

References

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