Journal of Sasang Constitutional Medicine (사상체질의학회지)

The Society Of Sasang Constitutional Medicine (사상체질의학회)
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Inhibitory effects of Yangdokbackhotang on the Immune Hypersensitive Reaction in skin transplant mice

양독백호탕(陽毒白虎湯)이 이식(移植) 피부(皮膚) 거부반응(拒否反應) 지연(遲延)에 미치는 영향(影響)

  • Park, Seong-Sik (Dept. of Sasang Constitutional Medicine. College of Oriental Medicine Dongguk University) ;
  • Jeon, Jun-Young (Dept. of Sasang Constitutional Medicine. College of Oriental Medicine Dongguk University)
  • 박성식 (동국대학교 한의과대학 사상체질과) ;
  • 전준영 (동국대학교 한의과대학 사상체질과)
  • Published : 2003.08.30
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Abstract

Objective: This study was carried out to evaluate the inhibitory effect on immme hypersensitive reaction by Yangdokbackhotang extract. methods: To study, We divided 4 weeks old rats into three groups of 20, which are the constrasive group with nothing treated, the skin transplated only, and the Yangdokbackhotang extract fed before skin transplantation. And did the experiment. Results: 1. The ear swelling in mice treated with YB noticeably decreased than only DNCB treated mice. 2. As shown in Table3, also results in a significant decrease of YB group than ST group in the number of positive cells of $NF-{\kappa}B$, COX-2, IL-12B, and ICAM-1. From the above results, it could be concluded that Yangdokbackhotang showed benificial immunosupressive effect on the hypersensitive reaction.

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