Korean Journal of Biological Psychiatry (생물정신의학)
- Volume 9 Issue 1
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- Pages.3-7
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- 2002
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- 1225-8709(pISSN)
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- 2005-7571(eISSN)
Serotonin(2A) Receptor Gene Promoter Polymorphism in Mood Disorder and Mood-Related Disorders
기분장애 및 기분관련장애에서 세로토닌 수용체 유전자 프로모터 다형성
- Chee, Ik-Seung (Department of Psychiatry, College of Medicine, Chungnam National University)
- 지익성 (충남대학교 의과대학 정신과학교실)
- Published : 2002.06.30
Abstract
Genes involved in the serotonin system are good candidates for the pathogenesis of mood disorder and mood-related disorders, such as eating disorder, obsessive-compulsive disorder, alcoholism, and suicide. Serotonin type 2A(5-HT2A) receptor gene promoter polymorphism(-1438A/G) has been reported. In this article, authors reviewed the literatures regarding association studies between -1438A/G and mood disorder and mood-related disorders. There are controversial results with limited data to date. Further researches on the -1438A/G in psychiatric disorders are required.
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