IMMUNE NETWORK
- 제2권4호
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- Pages.227-232
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- 2002
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- 1598-2629(pISSN)
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- 2092-6685(eISSN)
한국인 전신성홍반성루푸스 환자에서 HLA-DRB1, DQB1 대립유전자의 연관성 및 항인지질 항체와 항β2 Glycoprotein I 항체에 관한 연구
The Association of HLA-DRB1 and DQB1 Alleles and a Study of Anticardiolipin Antibody and Anti-β2 Glycoprotein I Antibody in Korean SLE Patients
- 이상곤 (성균관대학교 의과대학 삼성서울병원 진단검사의학교실) ;
- 차훈석 (성균관대학교 의과대학 삼성서울병원 내과학교실) ;
- 양윤선 (성균관대학교 의과대학 삼성서울병원 진단검사의학교실)
- Lee, Sang Gon (Department of Labolatory Medicine, Sungkyunkwan University College of Medicine, Samsung Medical Center) ;
- Cha, Hoon Suk (Department of Internal Medicine, Sungkyunkwan University College of Medicine, Samsung Medical Center) ;
- Yang, Yoon Sun (Department of Labolatory Medicine, Sungkyunkwan University College of Medicine, Samsung Medical Center)
- 발행 : 2002.12.31
초록
Background: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by diverse clinical manifestations and autoantibody production, which is known to be strongly influenced by genetic factors. Previous studies have revealed the associations of SLE with HLA class II alleles and antiphospholipid antibody system (anticardiolipin antibody (aCL) and anti-
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