Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Study on the Function of Hyunsamchungpye-eum on Anti-inflammatory and Anti-allergic Action

현삼청폐음이 항염 및 항알러지 작용에 관한 연구

  • Sea Jung Min (Departments of Classics, College of Oriental Medicine, Woosuk University) ;
  • Kim Jin Su (Department of Oriental Pathology, College of Oriental Medicine, Woosuk University) ;
  • Lee Kwang Gyu (Department of Oriental Pathology, College of Oriental Medicine, Woosuk University) ;
  • Ryuk Sang Won (Departments of Classics, College of Oriental Medicine, Woosuk University)
  • 서정민 (우석대학교 한의과대학 원전의사학교실) ;
  • 김진수 (우석대학교 한의과대학 병리학교실) ;
  • 이광규 (우석대학교 한의과대학 병리학교실) ;
  • 육상원 (우석대학교 한의과대학 원전의사학교실)
  • Published : 2002.02.01
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Abstract

The purpose of this research was to investigate effects of Hyunsamchungpye-eum(HSCPE) on the anti-inflammatory/anti-allergic reaction in vivo and in vitro. HSCPE reduced the acute hind paw edema induced by histamine, the permeability of evans blue into peritoneal cavity. HSCPE inhibited the passive cutaneous anaphylaxis reaction in rat, the lethal anaphylaxis and degranulation of peritoneal mast cells induced by compound 48/80 in mice, HSCPE did not affect the Arthus reaction, but decreased the delayed type hypersensitivity induced by SRBC, contact dermititis induced by DNFB. These results suggest that HSCPE have an anti-inflammatory and anti-allergic action.

Keywords

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