Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effects of the Fractionation of Sophorae Radix Water Extract on the Langendorff hearts

고삼 유기용매 분획층이 적출 심장에 미치는 영향

  • Kim Sang Beam (Department of physiology, college of oriental medicine, Wonkwang University) ;
  • Kwon Kang Beam (Department of physiology, college of oriental medicine, Wonkwang University) ;
  • Park Jun Su (Department of physiology, college of oriental medicine, Wonkwang University) ;
  • Park Gwan Ha (Department of Fish pathology, College of Ocean Science & Technology, Kunsan National University) ;
  • Ryu Do Gon (Department of physiology, college of oriental medicine, Wonkwang University)
  • 김상범 (원광대학교 한의과대학 생리학교실) ;
  • 권강범 (원광대학교 한의과대학 생리학교실) ;
  • 박준수 (원광대학교 한의과대학 생리학교실) ;
  • 박관하 (군산대학교 해양과학대학 어병학교실) ;
  • 류도곤 (원광대학교 한의과대학 생리학교실)
  • Published : 2002.02.01
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Abstract

The water extract of Sophorae radix was tested for its preventive effects against cardiovascular anaphylaxis elicited in experimental animals. H₂O and ethyl acetate fractionation of Sophorae radix water extract improved anaphylactic cardiac dysfunction in passively sensitized isolated guinea hearts: improvement was noted in the maximal contractile force, post-challenge contractile force, post-challenge coronary flow and creatine kinase change elevation. These results suggest that H₂O and ethyl acute fractionation of Sophorae radix water extract possesses anti-anaphylactic effect in cardiovascular system.

Keywords

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