Diagnosis of Hirschsprung's Disease of Neonate and Infant

신생아 및 영아기의 허쉬슈프렁병 진단

  • Kim, Dae-Yeon (Department of Surgery, University of Ulsan College of Medicine Asan Medical Center) ;
  • Kim, Seong-Chul (Department of Surgery, University of Ulsan College of Medicine Asan Medical Center) ;
  • Kim, Kyung-Mo (Department of Pediatrics, University of Ulsan College of Medicine Asan Medical Center) ;
  • Kim, Ellen Ai-Rhan (Department of Pediatrics, University of Ulsan College of Medicine Asan Medical Center) ;
  • Kim, Ki-Soo (Department of Pediatrics, University of Ulsan College of Medicine Asan Medical Center) ;
  • Kim, Jung-Sun (Department of Pathology, University of Ulsan College of Medicine Asan Medical Center) ;
  • Goo, Hyun-Woo (Department of Radiology, University of Ulsan College of Medicine Asan Medical Center) ;
  • Yoon, Chong-Hyun (Department of Radiology, University of Ulsan College of Medicine Asan Medical Center) ;
  • Kim, Jin-Cheon (Department of Surgery, University of Ulsan College of Medicine Asan Medical Center) ;
  • Pil, Soo-Young (Department of Pediatrics, University of Ulsan College of Medicine Asan Medical Center) ;
  • Kim, In-Koo (Department of Surgery, University of Ulsan College of Medicine Asan Medical Center)
  • 김대연 (울산대학교 의과대학 서울중앙병원 외과학교실) ;
  • 김성철 (울산대학교 의과대학 서울중앙병원 외과학교실) ;
  • 김경모 (울산대학교 의과대학 서울중앙병원 소아과학교실) ;
  • 김애란 (울산대학교 의과대학 서울중앙병원 소아과학교실) ;
  • 김기수 (울산대학교 의과대학 서울중앙병원 소아과학교실) ;
  • 김정선 (울산대학교 의과대학 서울중앙병원 병리과학교실) ;
  • 구현우 (울산대학교 의과대학 서울중앙병원 방사선과학교실) ;
  • 윤종현 (울산대학교 의과대학 서울중앙병원 방사선과학교실) ;
  • 김진천 (울산대학교 의과대학 서울중앙병원 외과학교실) ;
  • 피수영 (울산대학교 의과대학 서울중앙병원 소아과학교실) ;
  • 김인구 (울산대학교 의과대학 서울중앙병원 외과학교실)
  • Published : 2002.06.30

Abstract

Diagnosing Hirschsprung's disease is a clinical challenge. Hirschsprung's disease should be considered in any child who has a history of constipation dating back to the newborn period. We examined diagnostic methods and their results retrospectively in 37 neonates and infants who underwent both barium enema and anorectal manometry for the diagnosis of Hirschsprungs disease at Asan Medical Center between January 1999 and April 2001. Two radiologists and a surgeon repeatedly reviewed both of the diagnostic results. In anorectal manometry, thirty-four studies were in agreement with the definitive diagnosis, giving an overall diagnostic accuracy of 91.9 % (neonate; 100 %, infant; 85.7 %). The accuracy and specificity of barium enema was lower than those of anorectal manometry, but sensitivity was higher. There was no significant difference between the two methods. Both studies showed findings consistent with the final diagnosis. However, discordant results needed further evaluation or close observation to diagnose accurately. We conclude that Hirschsprungs disease should not be diagnosed by only one diagnostic method.

Keywords