HYPERICIN - BASED PHOTODYNAMIC THERAPY: COMPARATIVE ANTITUMOR ACTIVITY AND UPTAKE STUDIES IN MURINE EHRLICH ASCITE CARCINOMA.

Hypericin was found to exhibit the highest antitumoral activity in treating EAT by photodynamic therapy (PDT): Hypericin>HPde>PII>TPPS$_4$>ALA. Moreover, 25% of mice after Hyp-based PDT survived 4 months, if compare with control group. Antitumor activity of these photosensitizers was in rather clear correlation with accumulation potential.