Quantitative analysis of lipid hydroperoxides levels in peripheral organs of Juvenile Visceral Steatosis (JVS) Mice at 1 month of age

  • Seiichi Matsugo (Department of Applied Chemistry and Biotechnology, Faculty of Engineering, Yamanashi University) ;
  • Miki Saito (Department of Applied Chemistry and Biotechnology, Faculty of Engineering, Yamanashi University) ;
  • Fumihiko Yasui (Department of Applied Chemistry and Biotechnology, Faculty of Engineering, Yamanashi University) ;
  • Kazuo Sasaki (Division of Bio-information Engineering, Faculty of Engineering. Toyama University) ;
  • Li, Meng-Xian (Faculty of Medicine. Kagoshima University) ;
  • Masahisa Horiuchi (Faculty of Medicine. Kagoshima University) ;
  • Takeyori Saheki (Faculty of Medicine. Kagoshima University)
  • Published : 2002.08.01

Abstract

Juvenile visceral steatosis (JVS) mouse is an animal model of the systemic camitine deficiency. JVS mice first develop fatty liver following cardiac hypertrophy. hyperammonemia, etc. To clarify the relationship between fatty liver and other symptoms. lipid hydroperoxides levels of peripheral oragans in JVS mice at 1 month were determined by the use of phosphine derivatives. We also report here a new method to quantitate the lipid components level in fatty liver of JVS mice.

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