Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Chronic Lymphocytic Leukemia in a Dog

  • Jung, Seung-Woo (Veterinary Medical Teaching Hospital, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Choi, Eul-Soo (Veterinary Medical Teaching Hospital, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Lee, Jong-Bok (Veterinary Medical Teaching Hospital, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Hwang, Cheol-Young (Veterinary Medical Teaching Hospital, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Youn, Hwa-Young (Veterinary Medical Teaching Hospital, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Lee, Chang-Woo (Veterinary Medical Teaching Hospital, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Han, Hong-Ryul (Veterinary Medical Teaching Hospital, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University)
  • Published : 2002.12.01
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Abstract

Chronic Iymphocytic leukemia is a general disease that evolves over a longer duration and is characterized by more mature and well-differentiated Iymphocytes in blood and bone marrow than those seen in acute leukemia. This report presents a 2-year-old mix neutered male dog with seizure, ascites, and transmissible venereal tumor. Diagnostic works-up concluded chronic Iymphocytic leukemia. Chemotherapy composed of chlorambucil and prednisolone has been applied to the patient until now. Remission of almost manifestations was achieved, and the quality of life improved.

만성 림프구성 백혈병은 오랜기간에 걸쳐서 발전하는 전신질환이며, 급성 백혈병에서 보이는 것보다 더욱 성숙되고 잘 분화된 림프구가 혈액과 골수에 존재하는 것을 특징으로 한다. 본 증례보고에서는 발작, 복수의 임상 증상과 전염성 성병성 종양에 대한 치료경력이 있는 2년령의 거세된 잡종견을 다루고 있다. 여러 가지 진단 절차를 통하여 만성 림프구성 백혈병으로 진단내렸고, chlorambucil과 prednisolone을 이용한 항암치료를 현재까지 적용해 오고 있다. 초기내원 시 보였던 대부분의 증상에 대한 개선을 볼 수 있었으며, 환자의 삶의 질은 향상되었다.

Keywords

References

  1. J Vet Intern Med v.5 The effect of experimental cystitis and iatrogenic blood contamination on the urine protein/creatinine ratio in the dog Bagley RS(et al)
  2. J Am Soc Nephrol v.6 A longitudinal study of prognostic factors and therapy Baqu N(et al)
  3. Vet Pathol v.18 Well-differentiated lymphocytic leukemia in a dog; log-term survival without therapy Harvey JW;Terrell TG;Hyde DM(et al)
  4. J Am Vet Med Assoc v.117 Chronic lymphocytic leukemia in the dog Hodkins EM;Zinkl JG;Madewell BR
  5. J Am Vet Med Assoc chronic lymphocutic leukemia in the dog; 22 cases (1974-1984) Leifer CE;Mtus RE
  6. J Vet Intern Med v.7 The influence of naturally ocurring urinary tract infections on the urine protein/creatinine ratio in dogs Myers NC(et al)
  7. Blood v.46 Clinical staging of chronic lymphocytic leukemia Rai KR;Sawitsky A;Cronkite Ep(et al)
  8. Vet Clin Pathol v.21 Cytochemical staining characteristics of lymph nodes from normal and lymphoma affected dogs Raskin RE;Nipper MN
  9. Small Animal Internal Medicine(2nd ed) Couto. Leukemias Richard W. Nelson;C. Guillermo
  10. Textbook of Veterinary Internal Medicine(5th ed) Hematopoietic tumors Stephen J. Ettinger;Edward C. Feldman