Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
권호 표지

The Effects of Chromium Picolinate Supplementation on Glucose and Lipid Level in Rats Fed in High Fat Diet

Chromium Picolinate 보충이 고지방 식이를 섭취한 흰쥐의 체내 지질 농도에 미치는 영향

  • 오유진 (한양대학교 식품영양학과) ;
  • 장유경 (한양대학교 식품영양학과)
  • Published : 2002.10.01
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Abstract

This study aimed to investigate the effects of chromium picolinatec (CrP) supplementation on the glucose and lipid metabolism of rats. Five-week-old male Sprague-Dawley rats were fed a high-fat diet fir 110 days and further treated with CrP or placebos for 6 weeks. The effect of CrP supplementation on body weight, blood glucose, insulin and lipid levels was examined. The results suggested that body weight gain was not significantly different between the control and the CrP supplemented group. Plasma glucose, triglyceride and cholesterol levels in the CrP treated group significantly decreased compared to those of the control group (p < 0.05). The total lipid, triglyceride and cholesterol concentrations in the livers of the CrP treated group significantly decreased compared to those of the control group (p < 0.05). These results indicate that supplementation of chromium picolinate ran reduce triglyceride and glucose concentrations in the blood and total lipid and total cholesterol levels in the liver.

Keywords

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