한국어병학회지 (Journal of fish pathology)

  • 제15권1호
  • /
  • Pages.9-16
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  • 2002
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  • 1226-0819(pISSN)
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  • 2233-5412(eISSN)
한국어병학회 (The Korean Society of Fish Pathology)
권호 표지

잠복감염시의 해양버나바이러스의 세포내에서의 동태

Persistent Infection of Marine Birnavirus and its Status of Infection in Cells

  • 정성주 (여수대학교 수산생명의학과) ;
  • 오명주 (여수대학교 수산생명의학과)
  • 발행 : 2002.04.01
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초록

The objective of the study was to clarify the mechanism of persistent infection of marine birnavirus (MABV) in various nonpermissive cell lines. It was observed in CHSE-214, RTG-2 and RSBK-2 that the virus produced at high yield with typical cytopathic effect (CPE). On the contrary, the CPE was not produced in EPC, FHM and BF-2 cells. However amount of virus protein in both permissive and nonpermissive cell lines detected by ELISA was almost the same. Electron microscopy showed virions in permissive cells but not in nonpermissive cells. From the results, it is clear that virus protein and RNA were produced in nonpermissive cells as observed in permissive cells; however, assembly of the virus particles did not occur in nonpermissive cells.

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참고문헌

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