Journal of Microbiology and Biotechnology

  • 제12권4호
  • /
  • Pages.691-691
  • /
  • 2002
  • /
  • 1017-7825(pISSN)
  • /
  • 1738-8872(eISSN)
한국미생물·생명공학회 (The Korean Society for Microbiology and Biotechnology)
권호 표지

Two Neuroprotective Compounds from Mushroom Daldinia concentrica

  • Lee, In-Kyoung (Korea Research Institute of Bioscience and Biotechnology) ;
  • Bong-Sik Yun (Korea Research Institute of Bioscience and Biotechnology) ;
  • Young-Ho Kim (College of Pharmacy, Chungnam National University) ;
  • Ick-Dong Yoo (Korea Research Institute of Bioscience and Biotechnology)
  • 발행 : 2002.08.01
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초록

In the course of our screening for neuroprotective agents, a new compound (1) was isolated together with a known compound, caruilignan C (2), from the fruiting body of Daldinia concentrica. Their structures were determined on the basis of various spectral studies. Both compounds exhibited neuroprotective effect against iron-induced neurodegeneration in a primary culture of mouse cortical neurons.

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