Journal of Microbiology and Biotechnology
- Volume 12 Issue 4
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- Pages.691-691
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- 2002
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- 1017-7825(pISSN)
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- 1738-8872(eISSN)
Two Neuroprotective Compounds from Mushroom Daldinia concentrica
- Lee, In-Kyoung (Korea Research Institute of Bioscience and Biotechnology) ;
- Bong-Sik Yun (Korea Research Institute of Bioscience and Biotechnology) ;
- Young-Ho Kim (College of Pharmacy, Chungnam National University) ;
- Ick-Dong Yoo (Korea Research Institute of Bioscience and Biotechnology)
- Published : 2002.08.01
Abstract
In the course of our screening for neuroprotective agents, a new compound (1) was isolated together with a known compound, caruilignan C (2), from the fruiting body of Daldinia concentrica. Their structures were determined on the basis of various spectral studies. Both compounds exhibited neuroprotective effect against iron-induced neurodegeneration in a primary culture of mouse cortical neurons.