World research trends and problems in papers relating metal contamination level of herbal medicines

한약 금속오염과 관련된 세계적인 인식경향 -발표된 논문을 중심으로-

  • Lee Sun-Dong (Dept. of oriental preventive medicine, college of oriental medicine, Sangji university) ;
  • Lee Jung-Seok (Dept. of oriental preventive medicine, college of oriental medicine, Sangji university) ;
  • Park Kyung-Sik (Dept. of anatomy, college of oriental medicine, Sangji university)
  • 이선동 (상지대학교 한의과대학 예방의학교실) ;
  • 이정석 (상지대학교 한의과대학 예방의학교실) ;
  • 박경식 (상지대학교 해부학교실)
  • Published : 2002.06.29

Abstract

Metal problems in herbal medicine are not regulate properly by law and public management around world country until this time. General people belief as safety about herbal since natural material. And almost all persons can also purchase by their-self and use by self-prescription in reality. As this result herbal medicines can always occur acute and chronic toxicity by not proper use problems, side-effect and overdose. Heavy metal toxic diseases in historical view point was big accidents that didnot forget including minamata and itai-itai in Japan. These accident's teach to us must not use toxic metal level and not include or at least Pb Hg As Cd in all kind material use and intake by people, especially herbal. Herbal contamination research is beginner state that had not many papers until nowadays. Even if this pan had some papers, it had negative result and bigger and larger than problems level because of one way research trend of not many sample case-report and screening test of dried herbal form in chiefly. Many persons have afraid and risk thinking about herbal, animal and minerals since these cause. Further research related this subject will be needed at fact of epidemiology including case-control and cohort study for more precision research affecting in short and long term intake of oriental medicines

Keywords

References

  1. Complementary and alternative Medicine at the NIH v.3 program profile: International liaison brings global vision to OAM Anonymous
  2. N. Engl J Med v.328 unconventional medicine in the united states: prevalence coxts, and patterns of use Eisenberg, D.M.;Ronald, C.K.;Forster, C.(et al.)
  3. Scottish Medical Journal v.43 Possible toxicity of herbal remedies Bateman, J.;Chapman, R.D.;Simpson, D.
  4. American journal of industrial medicine v.20 A case of mistaken identify : Herbal medicine as a cause of lead toxicity Justine Smitherman;Harber, Philip
  5. International Journal of Environmental Health Research v.11 Heavy metal hazard of Asian traditional remedies Gregory, H.G.;Gray, H.;Richard, V.L.;Raymond, D.H.
  6. Human and experimental toxicology v.9 Herbal medicine as a cause of combined lead and arsenic poisoning Mitchell-Heggs, C.A.W.;Conway, M.;Cassar, J.
  7. JAMA v.271 Lead poisoning due to Hai Ge Fen - the porphyrin content of individual erythrocytes Steven, B.M.;Carol, M.N.;Susan, K.(et al.)
  8. Postgrad Med J v.70 Indian herbal remedies for diabetes as a cause of lead poisoning Keen, R.W.;Deacon, A.C.;Delves, H.T.;Moreton, I.A.;Frost, P.G.
  9. The medical J of Australia v.157 Lead poisoning from Indian herbal medicine (Ayurveda) David, W.D.;George, A.T.;Phillip, Y.P.;Raymond, A.L.
  10. N Engl J Med v.333 Toxic Metals in selected Traditional Chinese Medicinals Edgard, O.E.;Mann, M.J.;Bob, B.
  11. Vet Hum Toxicol v.34 Chinese patient medicine as a potential source of mercury poisoning - clinical reports- Elaine, K.Y.;Stanley, H.O.
  12. N. Engl J med v.333 no.12 Arsenic and mercury in traditional chinese herbal Balls Espinoza, E.O.;Mann, Mary-Jacque;Bleasdell, Bob
  13. Vet. Human Toxicol v.36 no.3 The prevalence use and Harmful potential of some chinese Herbal medicines in babies and children Thomas, Y.K. chan
  14. Nephrol Dial Transplant v.11 Multiple tubular dysfunction induced by mixed Chinese herbal medicine containing cadimium Wu, M.S.;Hong, J.J.;Yang, C.W.;Chien, H.C.
  15. Occup Environ Med v.55 Chinese herbal medicine, sibship, and blood lead in children Cheng, T.J.;Wong, R.H.;Lin, Y.P.;Hwang, Y.H.;Horng, J.J.;Wang, J.D.
  16. Drug safety v.23 Chinese proprietary medicine in Singapore-regulatory control of toxic heavy metal and undeclared drugs Koh, H.L.;Woo, S.O.
  17. The Medical J of Austrailia v.13 Arsenic poisoning from Anti-Ashmatic Herbal preparations Chong-Hay, Tay;Cheng-siang, Seah
  18. JAMA v.250 no.23 lead poisoning from Mexican folk Remedies Sankury(etc)
  19. Folk Remedy-Associated v.250 no.23 Folk Remedy-Associated lead poisoning in Hmong Children Levitt(etc)
  20. Journal of school health v.71 Alternative medicine: more than a harmless option Roland, J.L.
  21. Drug safety v.14 Fetal abnormalities and use of substances sold in herbal remedies shops Fernando, L.M.;Sara, S.C.
  22. 대한예방한의학회지 v.2 no.1 한약재의 안전성확보 및 관리방안 -오염경로및대책을 중심으로- 이선동;김명동;박경식
  23. Toxicology of metals Stanley, S. Brown;Yasushi Kordama
  24. Drug safety v.17 Traditional remedies and food supplements. A 5-year toxicological study(1991-1995) Debbis, S.;Christine, L.;Stoyko, K.;Virginia, M.
  25. Biological Trace Element Research v.54 Minor and trace elemental determination in the Indian herbal and other medicinal preparations Dhananjay L. Samudralwar;Amar, N.G.
  26. 한약재에 포함된 중금속의 다리기 전과 후의 농도 변화 연구 이선동;박해모;이장천;국윤범
  27. 오적산을 투여한 흰쥐의 간장${\cdot}$신장${\cdot}$골중 금속농도비교에 관한 연구-용량관계와 기전을 중심으로- 박철수
  28. 오적산을 투여한 흰쥐의 혈중 금속 농도비교에 관한 연구 이정렬
  29. 교정 방제대사전 포명총;강극명(주편)
  30. 교정 동의보감 원진희(외 8인)
  31. Ned Tijdschr Geneeskd v.138 Manngaanintoxicatie door hetgetbruik van Chien Pu Wan-tabletten M.C.T.F.M. DE Krom;A.M.H.P. Boreas;EN E.L.M. Hardy
  32. N Engl J Med v.339 Alternative medicine - the risk of untested and unregulated remedies Marcia, A.;Jerome, P.K.
  33. 생약의 잔류허용기준 및 시험방법(안) 식품의약안전청