Journal of Korean Neurosurgical Society

대한신경외과학회 (The Korean Neurosurgical Society)
권호 표지

두개강내압 상승 환자에서 저체온법의 유용성 - 임 상 연 구 -

Usefulness of Hypothermia Treatment in Patients with Increased Intracranial Pressure

  • 이종무 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
  • 안재성 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
  • 김정훈 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
  • 김창진 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
  • 권양 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
  • 이정교 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
  • 권병덕 (울산대학교 의과대학 서울중앙병원 신경외과학교실) ;
  • 전상룡 (울산대학교 의과대학 서울중앙병원 신경외과학교실)
  • Lee, Jong Moo (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Ahn, Jae Sung (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Kim, Jeong Hoon (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Kim, Chang Jin (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Kwon, Yang (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Lee, Jung Kyo (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Kwun, Byung Duk (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan) ;
  • Jeon, Sang Ryong (Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan)
  • 투고 : 2001.11.07
  • 심사 : 2001.11.28
  • 발행 : 2001.12.31
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초록

Objectives : The goal of this study is to evaluate the usefulness of mild hypothermia treatment in patients with increased intracranial pressure(ICP). Material and Method : From November 1999 to May 2001, 11 patients were treated with mild hypothermia ($32-34^{\circ}C$) in whom ICP maintained at higher than 20mmHg in spite of decompressive surgery and high dose barbiturate therapy. The patient's rectal temperature were lowered by external cooling. Hypothermia was maintained for not more than 7 days and then the patients were rewarmed slowly for 24 hours. If increased ICP persisted for 2 days of hypothermia, this treatment was continued for several days. The functional outcome of each patient was assessed according to Glasgow Outcome Scale(GOS). Results : All cases except two cases showed decrease of ICP after hypothermia therapy. In 1 case which was right middle cerebral artery(MCA) infarct, ICP re-increased after 24 hours and in another 1 case, ICP was not controlled initially. Among 11 cases, 3 cases showed favorable outcome. Conclusion : Mild hypothermia treatment in patients with increased ICP was effective in controlling ICP and mortality was so decreased. More clinical experience and controlled study was need to determine the effectiveness.

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