Rat Skin Permeation Characteristics of L-cystein to Common Permanent Wave Drug In Vitro

상용 퍼머넌트 웨이브 약제인 L-cystein의 랫드 피부 투과 특성

  • 김용렬 (대진대학교 이공대학 화학공학과) ;
  • 윤철훈 (명지대학교 공과대학 화학공학과) ;
  • 김낙주 (서울산업대학교 정밀화학과)
  • Published : 2001.11.01

Abstract

Hair will be persuit of beautifulness of human being in various permanent wave by many kinds of its drugs. Skin is based upon the hair which enroll the body of high living animals and have multiple membrane structure In this study used rat the effects of commercial permanent wave products to skin which are composed with L- cysteine and bases Results are as follow: the content of penetration 4 hors later with steady state and no significant changeable after 20 hours later. In cysteine groups, lag time and permeability coefficient of healthy skin is 2.22hr and 0.13$\mu\textrm{g}$/㎥ hr, lag time and permeability coefficient of old skin is 4.01 hr and 0.108 $\mu\textrm{g}$/㎥ hr . In conclusion of study lag time and permeability coefficient in old skin and wounded skin are faster than healthy skin. We notified that fine rinkle and rash of skin were changeable in the case of treating with permanent wave drugs than normal skin.

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